Stress heterogeneities in sheared type-I collagen networks revealed by Boundary Stress Microscopy

PloS One
Richard C ArevaloDaniel L Blair

Abstract

Disordered fiber networks provide structural support to a wide range of important materials, and the combination of spatial and dynamic complexity may produce large inhomogeneities in mechanical properties, an effect that is largely unexplored experimentally. In this work, we introduce Boundary Stress Microscopy to quantify the non-uniform surface stresses in sheared collagen gels. We find local stresses exceeding average stresses by an order of magnitude, with variations over length scales much larger than the network mesh size. The strain stiffening behavior observed over a wide range of network mesh sizes can be parameterized by a single characteristic strain and associated stress, which describes both the strain stiffening regime and network yielding. The characteristic stress is approximately proportional to network density, but the peak boundary stress at both the characteristic strain and at yielding are remarkably insensitive to concentration.

References

Dec 11, 1995·Physical Review Letters·F C MacKintoshP A Janmey
Jun 27, 2000·Biophysical Journal·C M LoY L Wang
Aug 19, 2000·Cellular and Molecular Life Sciences : CMLS·P Friedl, E B Bröcker
Feb 19, 2002·Trends in Cell Biology·Karen A Beningo, Yu-Li Wang
Feb 3, 2004·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·D A HeadF C MacKintosh
May 29, 2004·Science·M L GardelD A Weitz
May 13, 2005·Nature·Cornelis StormPaul A Janmey
Dec 31, 2005·Physical Review Letters·P R OnckE van der Giessen
Feb 21, 2006·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·B A Didonna, T C Lubensky
Oct 10, 2006·Physical Review Letters·Claus Heussinger, Erwin Frey
Dec 26, 2006·Nature Materials·Paul A JanmeyFred C MacKintosh
Aug 7, 2007·Physical Review Letters·Gavin A Buxton, Nigel Clarke
Sep 4, 2007·The European Physical Journal. E, Soft Matter·C Heussinger, E Frey
Oct 7, 2008·Biophysical Journal·Walter MickelGerd E Schröder-Turk
Mar 5, 2009·Physical Review Letters·Enrico Conti, Fred C Mackintosh
Jun 17, 2009·PloS One·David VaderLakshminarayana Mahadevan
Apr 16, 2010·Biomacromolecules·Kendra A ErkKenneth R Shull
May 21, 2010·Biophysical Journal·Norman Y YaoDavid A Weitz
Aug 11, 2010·Proceedings of the National Academy of Sciences of the United States of America·Ye XuEric R Dufresne
Oct 21, 2010·Biophysical Journal·Richard C ArevaloDaniel L Blair
Jun 16, 2011·Biomacromolecules·Izabela K PiechockaGijsje H Koenderink
Jan 10, 2012·Chaos·Richard C ArevaloDaniel L Blair
Mar 10, 2012·Physical Review Letters·C P BroederszF C Mackintosh
Oct 26, 2012·Biopolymers·Stéphanie Motte, Laura J Kaufman
Jan 29, 2013·Nature·Paul H J KouwerAlan E Rowan
Jun 29, 2013·Experimental Cell Research·Matthew S HallMingming Wu
Jul 5, 2013·The Review of Scientific Instruments·S K DuttaDaniel L Blair

❮ Previous
Next ❯

Citations

Jun 16, 2016·Chemical Society Reviews·Luis M De Leon RodriguezMargaret A Brimble
Aug 3, 2017·Proceedings of the National Academy of Sciences of the United States of America·Vikram RatheeJeffrey S Urbach
Jan 1, 2019·Cell Biology International·Han ZhaoQingjia Chi
Oct 26, 2016·Physical Biology·Long LiangYang Jiao
Jan 9, 2019·Physical Review. E·Brian BurkelJacob Notbohm
Jul 14, 2018·Physical Review Letters·Yuval MullaGijsje H Koenderink
May 20, 2020·Physical Review. E·Vikram RatheeRajesh Ganapathy
Jan 25, 2020·Physical Review Letters·Simone DussiJasper van der Gucht
Nov 15, 2016·Physical Review. E·A SharmaF C MacKintosh
Nov 23, 2017·Soft Matter·Yen H TranShelly R Peyton
May 22, 2019·Physical Review. E·Sadjad ArzashFred C MacKintosh
Jun 15, 2021·Soft Matter·Maria ProestakiJacob Notbohm
Jun 17, 2021·Soft Matter·Swarnadeep BakshiSayantan Majumdar
Oct 5, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Mehdi Bouzid, Emanuela Del Gado

❮ Previous
Next ❯

Methods Mentioned

BETA
rheology

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.