Stress-Induced and Diabetic Hyperglycemia Associated with Higher Mortality among Intensive Care Unit Trauma Patients: Cross-Sectional Analysis of the Propensity Score-Matched Population

International Journal of Environmental Research and Public Health
Meng-Wei ChangChing-Hua Hsieh

Abstract

This study was designed to measure the effect of stress-induced hyperglycemia (SIH) and diabetic hyperglycemia (DH) versus non-diabetic normoglycemia (NDN) on the outcomes of trauma patients in the intensive care unit (ICU). Diabetes mellitus (DM) was determined based on patient history and/or a hemoglobin A1c (HbA1c) level of &ge;6.5% at admission. The patients who had serum glucose levels of &ge;200 mg/dL in the absence or presence of DM were assigned into the groups SIH and DH, respectively. Diabetic normoglycemia (DN) and NDN were determined based on serum glucose levels of <200 mg/dL in patients with and without DM, respectively. Patients with burn injury or incomplete data were excluded. Detailed data of trauma patients in the ICU of a Level-I trauma center from 1 January 2009 to 31 December 2016 were retrieved from the database of the Trauma Registry System. These patients were classified into four exclusive groups, including NDN (n = 1745), DN (n = 306), SIH (n = 225) and DH (n = 206). The Pearson chi-square test was used to compare categorical data between groups. Continuous variables were compared using one-way analysis of variance along with the Games⁻Howell post hoc test. To decrease the confounding effect of the di...Continue Reading

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Citations

Dec 15, 2018·Journal of Nursing Care Quality·Lisa NeelonDonna M Miller
Sep 29, 2019·International Journal of Environmental Research and Public Health·Wei-Ti SuChing-Hua Hsieh
Nov 3, 2020·Diabetes/metabolism Research and Reviews·Hana'a Rayyan-AssiItamar Raz
Mar 6, 2021·Frontiers in Public Health·Jesús Chávez-ReyesBruno A Marichal-Cancino
Jul 9, 2021·Infection and Drug Resistance·Feng Guo, Haitao Shen

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