PMID: 3767514Oct 1, 1986Paper

Stress sharing between the sinus and leaflets of canine aortic valve

The Annals of Thoracic Surgery
M J ThubrikarJ D Deck

Abstract

A knowledge of the behavior of the aortic valve sinuses is necessary to the understanding of stress sharing between the sinuses and the leaflets. Radiopaque markers were placed on the sinuses and the leaflets of dogs during cardiopulmonary bypass, and the movement of the markers was studied using fluoroscopy. The center of the sinus moved radially during each cardiac cycle, but in an inconsistent manner. The sinus was under a dual influence: the passive influence of aortic pressure and the active influence of myocardial contraction. The longitudinal curvature of the sinus showed no dimensional change, whereas the radius of the circumferential curvature decreased by 15.7% from systole to diastole. In diastole, the stress in the sinus was 6.1 g/mm2 and was 24.3 g/mm2 circumferentially and 12.1 g/mm2 radially in the leaflet. Histologically, the main stress-bearing component of the leaflet was made up of thick, dense, collagenous fibers oriented circumferentially. These fibers curved into the sinus wall instead of inserting straight into the aortic wall, thereby suggesting that the high stress in the leaflet is shared with the sinus and that continuity of the circumferential stress exists between the leaflet and the sinus. The leaf...Continue Reading

References

Oct 1, 1977·The American Journal of Cardiology·M ThubrikarS P Nolan
Jul 1, 1973·Cardiovascular Research·B J BellhouseL Talbot
Sep 1, 1968·British Heart Journal·M Campbell
Nov 1, 1980·Circulation Research·M ThubrikarS P Nolan

❮ Previous
Next ❯

Citations

Mar 22, 2013·Annals of Biomedical Engineering·Sivakkumar ArjunonAjit P Yoganathan
Apr 13, 2011·Journal of Cardiovascular Translational Research·Paul SchoenhagenSandra S Halliburton
Jun 29, 2011·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Ismail YurekliAli Gurbuz
Jul 13, 2000·The Annals of Thoracic Surgery·K J GrandeK S Kunzelman
Nov 18, 2000·The Annals of Thoracic Surgery·G A El KhouryR A Dion
Mar 1, 1997·Journal of the American College of Cardiology·B F StewartC M Otto
Nov 7, 2000·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·M E EdepD L Brown
Jun 16, 2007·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jonathan T Butcher, Robert M Nerem
Jun 19, 2009·PloS One·Eli J WeinbergMohammad R K Mofrad
Jul 16, 2011·International Journal of Inflammation·Kartik BalachandranAjit P Yoganathan
Feb 13, 2014·The Journal of Thoracic and Cardiovascular Surgery·Carmelo MignosaAntonino S Rubino
Jun 5, 2001·The Annals of Thoracic Surgery·M J ThubrikarB L Fowler
Jan 1, 2005·Multimedia Manual of Cardiothoracic Surgery : MMCTS·Ruggero De PaulisLuigi Chiariello
Dec 26, 2015·The Journal of Thoracic and Cardiovascular Surgery·Joel PriceDuke E Cameron
Jan 23, 2013·The Annals of Thoracic Surgery·Takeshi KomodaMichael Huebler
Aug 2, 2011·The Annals of Thoracic Surgery·Nishant D PatelLuca A Vricella
Dec 29, 2015·Seminars in Thoracic and Cardiovascular Surgery·Carmelo MignosaAntonino S Rubino
Oct 11, 2015·The Journal of Thoracic and Cardiovascular Surgery·Kenton J Zehr
May 24, 2008·The Annals of Thoracic Surgery·Nishant D PatelDuke E Cameron
Jun 9, 2001·IEEE Transactions on Bio-medical Engineering·K J Grande-AllenK S Kunzelman
Nov 2, 2001·The Journal of Thoracic and Cardiovascular Surgery·K J Grande-AllenK S Kunzelman
Jul 26, 2006·The Annals of Thoracic Surgery·Nishant D PatelDuke E Cameron
Mar 25, 2000·The Journal of Thoracic and Cardiovascular Surgery·K J Grande-AllenK S Kunzelman
Jun 29, 1999·The Journal of Thoracic and Cardiovascular Surgery·R H MessierR A Hopkins
Apr 30, 2008·The Annals of Thoracic Surgery·Namrata GundiahElaine E Tseng
Mar 27, 2010·The Annals of Thoracic Surgery·Roland HetzerMichael Huebler
Sep 13, 2015·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Andrea SalicaRuggero De Paulis
Feb 13, 2015·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Marina FunayamaYasuhide Nakayama
Oct 16, 2012·Journal of the American College of Cardiology·Marc R DweckDavid E Newby
Jun 28, 2008·Journal of the American College of Cardiology·Gösta B PetterssonEugene H Blackstone
Apr 17, 2012·The Journal of Thoracic and Cardiovascular Surgery·Giuseppe PisaniRuggero De Paulis
Jan 23, 2003·Microscopy Research and Technique·Richard L LeaskJagdish Butany
Oct 19, 2017·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Bernhard VennemannDominik Obrist
Apr 1, 1996·Arteriosclerosis, Thrombosis, and Vascular Biology·K D O'BrienC M Otto
Mar 21, 2001·Circulation·E R MohlerF S Kaplan
Sep 8, 2006·The American Journal of Geriatric Cardiology·Michael D VanAuker
Nov 21, 2007·Cardiovascular Engineering·Eli J Weinberg, Mohammad Reza Kaazempur Mofrad
May 7, 2009·American Journal of Therapeutics·Rohit Seth Loomba, Rohit Arora

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.