Stressful Beginnings with Long-Term Consequences

Cell
Camila Rosat Consiglio, Petter Brodin

Abstract

Early-life stress can have long-term health consequences, but the mechanisms of this are unknown. In this issue of Cell, Hong et al. demonstrate one such mechanism linking perinatal corticosteroid exposure to reduced CD8+ T cell function later in life and impaired anti-cancer and anti-bacterial immune responses.

References

Jul 16, 2005·Endocrinology·M H VickersM Harris
Oct 28, 2005·The New England Journal of Medicine·Matthew W Gillman
Oct 12, 2013·Nature Reviews. Immunology·Vanja LazarevicGraham M Lord
Feb 11, 2015·Annual Review of Immunology·Zvi Grossman, William E Paul
Oct 2, 2015·Science Translational Medicine·Marie-Claire ArrietaB Brett Finlay
Aug 25, 2018·Cell·Axel OlinPetter Brodin

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Citations

Jan 15, 2021·Nature Medicine·Petter Brodin
Aug 7, 2021·Brain Sciences·Noriyoshi UsuiShoichi Shimada

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