PMID: 1206431Dec 1, 1975Paper

Striato-nigral degeneration. Report of a case with an unusually short course and multiple system degenerations

Journal of the Neurological Sciences
F BuonannoN Rizzuto

Abstract

A 50-year-old white woman with an 8-month history of Parkinson's syndrome which did not respond to levodopa therapy was found on pathological examination to have the topographical lesions of striato-nigral degeneration. In addition to those characteristic lesions, an associated degeneration of the optic pathways, from the level of the optic nerve to the geniculo-collicular fibers, of the corticospinal tract and of the olivo-dentate axis, were found. While offering further evidence for the concept of "multiple system degeneration", no pathogenetic relationship either to previous cases of striato-nigral degeneration or to other multiple system degenerations is implied.

Citations

Jan 1, 1991·Acta Neuropathologica·D S Horoupian, D W Dickson
Sep 1, 1991·Journal of Clinical and Experimental Neuropsychology·E V SullivanA Pfefferbaum
Mar 1, 1997·Movement Disorders : Official Journal of the Movement Disorder Society·G K WenningN P Quinn

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