Stroke: a double-edged sword for cleaving clots?

Current Biology : CB
D C Anthony, V H Perry

Abstract

The discovery that tissue plasminogen activator can promote neuronal degeneration has uncovered a novel pathway leading to neuronal cell death and raises important issues concerning the use of tissue plasminogen activator as a thrombolytic therapy for stroke.

References

Dec 14, 1995·The New England Journal of Medicine·UNKNOWN National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group
Jul 1, 1995·Stroke; a Journal of Cerebral Circulation·J R BrorsonR J Miller
Jul 1, 1996·Glycobiology·E Ruoslahti
Nov 14, 1996·Nature·S E TsirkaS Strickland

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Citations

Dec 16, 1998·Research in Immunology·V H PerryS Betmouni
Oct 29, 2000·Annals of Emergency Medicine·R W Neumar
Jun 11, 2003·Annals of the New York Academy of Sciences·S H Vollmer
Jan 31, 2003·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Patrizia FerrettiPaul O'Neill

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