Stroke and renal dysfunction

European Journal of Internal Medicine
T Hojs Fabjan, Radovan Hojs

Abstract

Stroke is the most frequent neurological disease and represents a continuously evolving medical and social problem. Chronic kidney disease (CKD) is also an important worldwide public health problem. Renal dysfunction carries a substantial risk of cardiovascular morbidity and mortality and an independent, graded association between renal function and cardiovascular events was found. In the last 15years the link between CKD and cerebrovascular disease has become more apparent. Patients with end stage renal disease treated with maintenance hemodialysis have a much higher incidence of stroke than the general population and stroke is one of the major causes of death in these patients. Nowadays ischemic subtype of stroke is present in approximately 70% of dialysis patients. In population based studies conflicting results have been reported about the association between stroke and CKD before replacement therapy. However, in high risk patients, defined by the presence of either cardiovascular disease or cardiovascular risk factors, different stages of CKD are clearly associated with subsequent stroke. In patients with stroke the exact prevalence of renal dysfunction is not known. Reported prevalence from a few published studies is up t...Continue Reading

References

Feb 1, 1986·Archives of Neurology·H P AdamsR J Corry
Aug 1, 1986·Archives of Neurology·L Fisher, H Kotsoris
Feb 9, 1984·The New England Journal of Medicine·C E Mogensen
Nov 1, 1993·Kidney International·K IsekiK Fukiyama
Jan 1, 1997·Stroke; a Journal of Cerebral Circulation·T NakayamaH Tanaka
Jun 19, 1998·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M KawamuraT Eto
Nov 20, 1998·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Andrew S Levey
Nov 20, 1998·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·R N FoleyMark J Sarnak
Jun 16, 1999·Archives of Neurology·N B BeamerM Wynn
Jun 22, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·A P GuérinF Metivier
Sep 30, 2000·Artificial Organs·Radovan Hojs
Aug 31, 2001·Journal of the American College of Cardiology·M G ShlipakHeart and Estrogen/progestin Replacement Study (HERS) Investigators
Jun 8, 2002·Stroke; a Journal of Cerebral Circulation·Ronald S MacWalterRouling Chen
Jun 29, 2002·Journal of the American Academy of Nurse Practitioners·Mary Jo Goolsby
Feb 18, 2003·Clinical Transplantation·Anna OliverasJosep Lloveras
Jul 9, 2003·Kidney International·Stephen L SeligerCatherine O Stehman-Breen
Apr 22, 2004·Journal of the American Society of Nephrology : JASN·Daniel E WeinerMark J Sarnak
Sep 24, 2004·The New England Journal of Medicine·Nagesh S AnavekarMarc A Pfeffer
Sep 24, 2004·The New England Journal of Medicine·Alan S GoChi-yuan Hsu
Jul 22, 2005·The New England Journal of Medicine·C WannerGerman Diabetes and Dialysis Study Investigators
Oct 29, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Emma PrestonEdwina A Brown
Nov 3, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Mhairi SigristChristopher W McIntyre
Dec 27, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·James A DelmezHemodialysis (HEMO) Study Group
Jul 11, 2006·Journal of the American Society of Nephrology : JASN·Dick de ZeeuwRobert H Henning
Mar 31, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Masaaki NakayamaYutaka Imai
Aug 28, 2007·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Meghan J ElliottRachel M Holden
Oct 19, 2007·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·T Hojs FabjanB Pecovnik Balon
Oct 27, 2007·Stroke; a Journal of Cerebral Circulation·Michiel J BosMonique M B Breteler
Dec 1, 2007·Stroke; a Journal of Cerebral Circulation·M Arfan IkramMonique M B Breteler
Jan 19, 2008·Artificial Organs·Robert EkartBreda Pecovnik Balon
Apr 4, 2008·Clinical Journal of the American Society of Nephrology : CJASN·Krista L LentineDaniel C Brennan
Jul 1, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Manjula Kurella TamuraWilliam McClellan
Jul 19, 2008·Stroke; a Journal of Cerebral Circulation·Ewoud J van DijkMonique M B Breteler
Aug 30, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·George TsagalisKonstantinos N Vemmos
Feb 3, 2009·Stroke; a Journal of Cerebral Circulation·Gilad YahalomDavid Tanne
Feb 28, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·KDOQI Work Group
Apr 1, 2009·The New England Journal of Medicine·Bengt C FellströmAURORA Study Group
Apr 3, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Seiichi MatsuoCollaborators developing the Japanese equation for estimated GFR
Apr 21, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Stephen M SozioRulan S Parekh
Aug 25, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Stephen L Seliger
Dec 1, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Varun AgrawalPeter A McCullough
May 15, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Carmen Sánchez-PeralesAntonio Liébana
Oct 5, 2010·BMJ : British Medical Journal·Meng LeeBruce Ovbiagele
Oct 5, 2010·BMJ : British Medical Journal·Vlado Perkovic, Alan Cass
Oct 12, 2010·Stroke; a Journal of Cerebral Circulation·Meng LeeBruce Ovbiagele
Nov 26, 2010·Journal of the Neurological Sciences·Bruce Ovbiagele
Jan 15, 2011·Journal of the American Society of Nephrology : JASN·Wolfgang C WinkelmayerSoko Setoguchi
Feb 8, 2011·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Yuuko TsukamotoShigeharu Takagi
Aug 13, 2011·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Yasumasa YamamotoIchiro Akiguchi
Aug 17, 2012·The New England Journal of Medicine·Jonas Bjerring OlesenChristian Torp-Pedersen
Sep 14, 2012·Journal of Thrombosis and Haemostasis : JTH·G OcakK J Jager
Oct 26, 2012·Expert Opinion on Drug Safety·Imtiaz SalimAmar M Salam
Nov 2, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Deborah ZimmermanCatherine M Clase
Nov 21, 2012·Expert Opinion on Drug Safety·Simonetta Genovesi, Antonio Santoro
Feb 23, 2013·Cerebrovascular Diseases·Albert PowerDiane Ames
Jun 4, 2013·Lancet·Vivekanand JhaChih-Wei Yang
Jun 12, 2013·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Khai P NgCharles J Ferro

Citations

Mar 20, 2015·Wiener klinische Wochenschrift·Tanja Hojs Fabjan, Radovan Hojs
Sep 12, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Jean-Marc ChillonBénédicte Stengel
Jul 25, 2018·Toxins·Maryam AssemLucie Hénaut
Oct 9, 2019·Journal of Stroke·Nuria P Torres-AguilaAcute Endophenotypes Group of the International Stroke Genetics Consortium (ISGC)
Jun 26, 2020·Frontiers in Cardiovascular Medicine·Marius MiglinasArturas Vinikovas
May 26, 2018·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Dan LiuPeter Nordbeck
Sep 27, 2020·The European Journal of Neuroscience·Birva ShahPallab Bhattacharya

Related Concepts

Indirect Thrombin Inhibitors
Hemodialysis
Kidney Failure, Chronic
Thrombolytic Therapy
Acute Cerebrovascular Accidents
Chronic Kidney Insufficiency
Cardiovascular Diseases
Cerebrovascular Disorders
Cessation of Life
Dialysis Procedure

Related Feeds

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Carotid Artery Diseases

Carotid artery disease is a group of pathological conditions of the carotid artery. Discover the latest research on carotid artery disease here.

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.