Stroke Symptoms With Absence of Recognized Stroke Are Associated With Cognitive Impairment and Depressive Symptoms in Older Adults With Diabetes

Journal of Geriatric Psychiatry and Neurology
Jesse S PasslerMichael Crowe

Abstract

Self-reported stroke symptoms may represent unrecognized cerebrovascular events leading to poorer cognitive and mental health. We examined relationships between stroke symptoms, cognitive impairment, and depressive symptoms in a high-risk sample: 247 adults aged ≥65 with diabetes. Stroke symptoms were assessed using the Questionnaire for Verifying Stroke-free Status, cognitive impairment was measured with the modified Telephone Interview for Cognitive Status, and depressive symptoms were measured using the 15-item Geriatric Depression Scale. In 206 participants without history of stroke/transient ischemic attack, 27.7% reported stroke symptoms, with sudden loss of comprehension most frequently reported (11.7%). Having >1 versus 0 stroke symptoms was associated with greater odds of cognitive impairment (odds ratio = 3.04, 95% confidence interval 1.15-8.05) and more depressive symptoms (b= 2.60,P< .001) while controlling for age, race, gender, education, diabetes duration, diabetes severity, and cardiovascular comorbidities. Better recognition and treatment of cerebrovascular problems in older adults with diabetes may lead to improved cognition and mental health.

References

Oct 6, 2001·Stroke; a Journal of Cerebral Circulation·W J JonesJ F Meschia
Apr 4, 2003·International Journal of Geriatric Psychiatry·Celeste A de JagerRobert Clarke
Jan 7, 2004·Cerebrovascular Diseases·James F MeschiaPeter C O'Brien
Mar 17, 2004·Journal of Affective Disorders·Alan J ThomasJohn T O'Brien
Mar 25, 2008·Annals of Neurology·Virginia J HowardCamilo R Gomez
Sep 26, 2008·Neuropsychology Review·M Maria Glymour, Jennifer J Manly
Dec 17, 2009·Epidemiology·M Arfan IkramMonique M B Breteler
Aug 17, 2010·Diabetologia·A NouwenUNKNOWN European Depression in Diabetes (EDID) Research Consortium
Oct 5, 2010·Journal of the Neurological Sciences·José A Luchsinger
May 4, 2011·Nature Reviews. Neurology·Amy L Byers, Kristine Yaffe
Oct 13, 2011·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Kannayiram Alagiakrishnan, Anne Sclater
Mar 22, 2012·Journal of Alzheimer's Disease : JAD·José A Luchsinger
Jun 16, 2012·American Journal of Public Health·Carl J CaspersenAnn L Albright
Aug 10, 2012·Neurology·Manjula Kurella TamuraBrigitte Schiller
Feb 27, 2013·Molecular Psychiatry·W D TaylorG S Alexopoulos
Jun 5, 2013·Stroke; a Journal of Cerebral Circulation·Virginia J Howard
Aug 13, 2013·Current Psychiatry Reports·Bibilola D Oladeji, Oye Gureje
Jul 11, 2014·JAMA : the Journal of the American Medical Association·Lee DucatBarbara J Anderson
Aug 17, 2014·The Lancet. Diabetes & Endocrinology·Edward W GreggTheodore J Thompson
Dec 19, 2015·Journal of Diabetes Research·LaRita C JonesMichael Crowe

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