Stroke volume variation during acute normovolemic hemodilution

Anesthesia and Analgesia
Gudrun KungysNeal W Fleming

Abstract

The intravascular volume of surgical patients should be optimized to avoid complications associated with both overhydration and underresuscitation. In patients undergoing intraoperative acute normovolemic hemodilution, we investigated whether stroke volume variation (SVV) derived from an arterial pressure-based cardiac output (CO) monitor system (FloTrac/Vigileo, Edwards Lifesciences, Irvine, CA) tracked the changes associated with blood removal and replacement. We further evaluated the correlations between SVV and 3-dimensional (3D) transesophageal echocardiographic (TEE) left ventricular (LV) volume measurements. Twenty-five patients had procedures during which acute normovolemic hemodilution was a planned part of the intraoperative management. We defined 7 measurement timepoints: baseline, after the removal of 5%, 10%, and 15% of the estimated blood volume (EBV) and after replacement with an equal volume of 6% hetastarch to -10%, -5%, and baseline EBV. At each timepoint, heart rate and systolic, diastolic, and mean arterial blood pressure were obtained from standard monitors, CO and SVV measurements were obtained from the FloTrac/Vigileo monitor, and TEE images were recorded for subsequent off-line reconstruction and determi...Continue Reading

References

Dec 23, 2003·Journal of Cardiothoracic and Vascular Anesthesia·Marina JamnickiDonat R Spahn
Jan 14, 2004·American Journal of Respiratory and Critical Care Medicine·Sheldon Magder
Jun 15, 2004·Lancet·Frederick A MooreErnest E Moore
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Dec 14, 2006·Critical Care : the Official Journal of the Critical Care Forum·Mehrnaz Hadian, Michael R Pinsky
Feb 10, 2007·Journal of Cardiothoracic and Vascular Anesthesia·Gerard R Manecke, William R Auger
Sep 21, 2007·Critical Care : the Official Journal of the Critical Care Forum·William T McGeeLori Kozikowski
Oct 2, 2007·Journal of Cardiothoracic and Vascular Anesthesia·Gerard R Manecke
Oct 2, 2007·Journal of Cardiothoracic and Vascular Anesthesia·Suraphong LorsomradeeStefan G De Hert
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Jun 24, 2008·Critical Care : the Official Journal of the Critical Care Forum·Christoph K HoferAndreas Zollinger

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Citations

Jun 4, 2011·Annals of Cardiac Anaesthesia·Amrik Singh, Joseph F Antognini
Dec 2, 2015·Anaesthesia·R Gupta, T J Gan
Aug 4, 2015·BioMed Research International·Claudia M SantosaNeal W Fleming
Apr 22, 2015·Perioperative Medicine·Lais Helena Camacho NavarroGeorge C Kramer
Nov 14, 2014·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Timothy E MillerMichael Mythen

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