Strong light-matter interactions: a new direction within chemistry

Chemical Society Reviews
Manuel HertzogKarl Börjesson


It is possible to modify the chemical and physical properties of molecules, not only through chemical modifications but also by coupling molecules strongly to light. More intriguingly, strong coupling between molecules and light is possible even without the presence of a photon. The phenomenon that makes this possible is called vacuum fluctuations, which is the finite zero point energy of the quantized electromagnetic field inside an optical cavity. The light-matter coupling, which can be as large as 1 eV (100 kJ mol-1), leads to the formation of new hybrid states, called polaritons. The formed hybrid states can be viewed as a linear combination of light (vacuum field) and matter (molecules), thus completely changing the energy landscape of the system. Using vacuum fluctuations, strong light-matter interactions have for instance been used to change chemical reactivity, charge conductivity, excited state relaxation pathways and rates of chemical reactions of organic molecules. In this review a brief history of the field is given, followed by a theoretical framework, methods of analysis, and a review of accomplishments. Finally, a personal reflection on the future perspectives and applications within this field is given.


Jun 15, 1994·Physical Review. B, Condensed Matter·R HoudréC Weisbuch
Mar 30, 1987·Physical Review Letters·D J HeinzenM S Feld
Jul 17, 1989·Physical Review Letters·M G RaizenH J Carmichael
Feb 24, 1992·Physical Review Letters·R J ThompsonH J Kimble
Dec 2, 1996·Physical Review Letters·D M WhittakerJ S Roberts
Oct 5, 2002·Science·Hui DengYoshihisa Yamamoto
Aug 15, 2003·Nature·Kerry J Vahala
Dec 16, 2003·Proceedings of the National Academy of Sciences of the United States of America·Hui DengYoshihisa Yamamoto
May 1, 2004·Annual Review of Physical Chemistry·M A L Marques, E K U Gross
Aug 25, 2004·Physical Review Letters·J BellessaJ Mugnier
Aug 11, 2005·Physical Review Letters·Jonathan R TischlerArto Nurmikko
Sep 29, 2006·Nature·J KasprzakLe Si Dang
Dec 13, 2006·Physical Review Letters·Lambert K van VugtDaniël Vanmaekelbergh
Jun 1, 2007·Nature·Leonid V Butov
Jul 14, 1995·Science·M H AndersonE A Cornell
Aug 4, 1972·Science·P W Anderson
Sep 7, 2007·Applied Optics·Fengying Ma, Xingyuan Liu
Oct 13, 2007·Physical Review Letters·Hui DengYoshihisa Yamamoto
Dec 1, 1948·Bulletin of Entomological Research·A H PARKER
Sep 4, 2008·Physical Review Letters·A P D LoveLe Si Dang
Oct 15, 2008·Physical Review Letters·S Kéna-CohenS R Forrest
Oct 15, 2008·Physical Review Letters·J J BaumbergN Grandjean
Mar 17, 2010·Nano Letters·Andrea SplendianiFeng Wang
Aug 25, 2010·Nature Materials·Boris Luk'yanchukChong Tow Chong
Jan 15, 2011·Physical Review Letters·Kin Fai MakTony F Heinz
Jan 15, 2011·Physical Review Letters·Y TodorovC Sirtori
Feb 16, 2011·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Barry M Garraway
Feb 25, 2011·Nature·K R BrownD J Wineland
May 6, 2011·Chemical Reviews·Naomi J HalasPeter Nordlander
Jun 15, 2011·Physical Review Letters·T SchwartzT W Ebbesen
Jul 26, 2011·Chemical Reviews·V M AgranovichM Litinskaya
Aug 6, 2011·Science·Haruka Tanji-SuzukiVladan Vuletić
Jan 12, 2012·Angewandte Chemie·James A HutchisonThomas W Ebbesen
Jan 28, 2012·The Journal of Chemical Physics·Eric R Bittner, Carlos Silva

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Methods Mentioned

two hybrid
surface plasmon resonance

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