Strontium and caries: a long and complicated relationship

Caries Research
Frank Lippert, Anderson Hara

Abstract

Investigations into the role of strontium (Sr) in caries prevention have attracted great interest in the research community in the past, with their peak in the 1970-80s. To this date, no clear indication of the relative importance of Sr in caries prevention has been provided. A vast number of animal caries, epidemiological and mechanistic studies have been conducted. Although there is much discrepancy, the majority of studies suggest that Sr exhibits some cariostatic properties, predominantly in the presence of fluoride. An optimum Sr concentration of 5-10 ppm in drinking water has been proposed as a direct result of several epidemiological caries studies. Despite these results, no direct link can be established between Sr and caries prevention as, to date, no relevant, randomized controlled trials have been reported. The extrapolation of potential cariostatic properties of Sr from epidemiological studies is difficult due to the co-presence of several other trace elements in the water of the study areas, with many of these elements being attributed cariostatic properties in their own right. Furthermore, the role of caries risk factors was not taken into consideration. There is a clear need for further research, especially on th...Continue Reading

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Citations

Mar 6, 2015·Dental Materials Journal·Yoshiki FunatoHidehiko Sano
Oct 12, 2016·PloS One·Piyaphong PanpisutAnne Margaret Young
Sep 3, 2014·Experimental Biology and Medicine·Martin Jj RonisThomas M Badger
Aug 2, 2019·Journal of Conservative Dentistry : JCD·Fatih Tulumbacı, Aylin Akbay Oba
Jan 10, 2014·International Dental Journal·Jonathan CreethKatherine Govier
Jan 10, 2014·International Dental Journal·Cynthia Pine

Related Concepts

Cariostatic Effect
Carious Dentin
Caries Resistance, Dental
Fluorides
Strontium
Trace Elements
Epidemiologic Studies
Dental Caries
Research
Controlled Clinical Trials, Randomized

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