Strontium-containing hydroxyapatite bioactive bone cement in revision hip arthroplasty

Biomaterials
G X NiK D K Luk

Abstract

Clinical outcome of cemented implants to revision total hip replacement (THR) is not as satisfactory as primary THR, due to the loss of bone stock and normal trabecular pattern. This study evaluated a bioactive bone cement, strontium-containing hydroxyapatite (Sr-HA) bone cement, in a goat revision hip hemi-arthroplasty model, and compared outcomes with polymethylmethacrylate (PMMA) bone cement. Nine months after operation, significantly higher bonding strength was found in the Sr-HA group (3.36+/-1.84 MPa) than in the PMMA bone cement group (1.23+/-0.73 MPa). After detached from the femoral component, the surface of PMMA bone cement mantle was shown relatively smooth, whereas the surface of the Sr-HA bioactive bone cement mantle was uneven, by SEM observation. EDX analysis detected little calcium and no phosphorus on the surface of PMMA bone cement mantle, while high content of calcium (14.03%) and phosphorus (10.37%) was found on the surface of the Sr-HA bone cement mantle. Even higher content of calcium (17.37%) and phosphorus (10.84%) were detected in the concave area. Intimate contact between Sr-HA bioactive bone cement and bone was demonstrated by histological and SEM observation. New bone bonded to the surface of Sr-HA c...Continue Reading

References

Nov 1, 1988·Clinical Orthopaedics and Related Research·Y DohmaeR B Gustilo
Mar 1, 1997·The Journal of Bone and Joint Surgery. British Volume·R P KatzR C Johnston
Nov 26, 1999·Journal of Biomedical Materials Research·H FujitaT Nakamura
Nov 9, 2002·Biomaterials·J D J EldridgeA E Goodship
Jan 30, 2004·The New England Journal of Medicine·Pierre J MeunierJean-Yves Reginster
Feb 6, 2004·Journal of Biomedical Materials Research. Part a·C T WongJ C Y Leong
Jul 19, 2005·Biomaterials·Andrew D SpeirsClive P Duncan
Aug 9, 2005·The Journal of Bone and Joint Surgery. American Volume·Umasuthan SrikumaranEdward F McCarthy

❮ Previous
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Citations

Aug 4, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Sophie VerrierAndreas Boger
Aug 16, 2008·Journal of Materials Science. Materials in Medicine·L HernándezI Goñi
Sep 4, 2009·Journal of Materials Science. Materials in Medicine·Guo X NiWilliam W Lu
Mar 3, 2011·Journal of Materials Science. Materials in Medicine·Guo-Xin NiWilliam W Lu
Mar 6, 2012·Journal of Materials Science. Materials in Medicine·Jennifer H ShepherdSerena M Best
Sep 10, 2013·Trends in Biotechnology·Susmita BoseAmit Bandyopadhyay
Mar 4, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Vania Blasques BuenoDenise Freitas Siqueira Petri
Jun 9, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Wen-Ta SuTe-Yang Huang
May 9, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Wen-Ta SuChih-Ming Chou
Feb 11, 2010·Acta Biomaterialia·Guilhem RomieuPhilippe Boudeville
Dec 11, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Wen-Ta SuTe-Yang Huang
Jan 13, 2009·Acta Biomaterialia·H B PanW W Lu
Aug 8, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Huan ZhouLinhong Deng
May 18, 2007·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·G X NiK D K Luk
Jul 4, 2007·Journal of Biomedical Materials Research. Part a·G X NiK D K Luk
Jun 26, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Gladius Lewis
Aug 7, 2008·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Lidia HernándezJulio San Román
Nov 25, 2011·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Guo-Xin NiHao-Bo Pan
Jun 15, 2012·Journal of Biomedical Materials Research. Part a·Meili ZhangJiang Chang
Apr 5, 2013·Journal of Biomedical Materials Research. Part a·Silvia LopaMatteo Moretti
Mar 19, 2016·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Jithendra T B RatnayakeGeorge J Dias
Jan 28, 2009·Journal of Biomedical Materials Research. Part a·Alejandro A GorustovichJosé M Porto López
Apr 22, 2015·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Yunfeng LiJing Hu
Jul 28, 2012·Journal of Tissue Engineering and Regenerative Medicine·J ChouB Ben-Nissan
Nov 24, 2011·Bone·Paula LinderbäckPer Aspenberg
Mar 26, 2016·Journal of Biomedical Materials Research. Part a·Zeinab Tahmasebi BirganiPamela Habibovic
Sep 11, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Céline Aubrun-FillâtrePhilippe Hivart
Dec 8, 2007·Acta Biomaterialia·Elena LandiAnna Tampieri
Oct 14, 2019·Journal of Materials Science. Materials in Medicine·Ali AleneziAnn Wennerberg
Feb 28, 2020·International Journal of Nanomedicine·Corina GarboMaria Tomoaia-Cotisel
Apr 4, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Cairong LiLing Qin
Jun 6, 2017·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·I GoñiM Gurruchaga
Jun 21, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Matthias Schumacher, Michael Gelinsky

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