Structural analysis of ruthenium-arene complexes using ion mobility mass spectrometry, collision-induced dissociation, and DFT

Dalton Transactions : an International Journal of Inorganic Chemistry
Izabella CzerwinskaEdwin De Pauw

Abstract

Ion mobility mass spectrometry (IM-MS) and collision-induced dissociation (CID) techniques were used to investigate the influence of the phosphine ligand on the physicochemical properties of [RuCl2(p-cymene)(PCy3)] (), [RuCl2(p-cymene)(PPh3)] (), and [RuCl2(p-cymene)(PTA)] () in the gas phase (PTA is 1,3,5-triaza-7-phosphaadamantane). Electrospray ionization of complexes and led to the corresponding [RuCl(p-cymene)(PR3)](+) ions via the dissociation of a chlorido ligand, whereas RAPTA-C () afforded two molecular ions by in-source oxidation ([Ru(III)Cl2(p-cymene)(PTA)](+)) or protonation ([RuCl2(p-cymene)(PTA+H)](+)). Control experiments showed that the balance between these two ionization paths was strongly influenced by the nature of the solvent used for infusion. Collision cross sections (CCSs) of the four molecular ions accurately reflected the variations of steric bulk inferred from the Tolman steric parameters (θ) of the phosphine ligands. Moreover, DFT calculations combined with a model based on the kinetic theory of gases (the trajectory method of the IMoS software) afforded reliable CCS predictions. The almost two times higher dipole moment of [RuCl2(p-cymene)(PTA+H)](+) (μ = 13.75 D) compared to [Ru(III)Cl2(p-cymene)(P...Continue Reading

References

Dec 13, 2001·Chemical Reviews·M KamigaitoM Sawamoto
Dec 26, 2001·Chemical Reviews·K Matyjaszewski, J Xia
May 9, 2002·Mass Spectrometry Reviews·N B Cech, C G Enke
Jun 10, 2005·Journal of Medicinal Chemistry·Claudine ScolaroPaul J Dyson
Oct 7, 2005·Mass Spectrometry Reviews·Thomas E Wales, John R Engen
Feb 24, 2007·Journal of Pharmaceutical and Biomedical Analysis·David Q LiuPaul A MacGregor
Aug 19, 2007·Analytical Chemistry·Gary J Van Berkel, Vilmos Kertesz
Jan 18, 2008·Journal of Mass Spectrometry : JMS·Abu B KanuHerbert H Hill
Jul 5, 2008·Nature Protocols·Brandon T RuotoloCarol V Robinson
Oct 31, 2008·Talanta·Mahmoud Tabrizchi, Fereshteh Rouholahnejad
Mar 17, 2009·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Angela CasiniLuigi Messori
Mar 20, 2009·Journal of the American Society for Mass Spectrometry·Jonathan P WilliamsPeter J Sadler
Jul 21, 2009·Journal of the American Society for Mass Spectrometry·Tzipporah M KerteszDavid F Grant
Mar 10, 2010·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Michael GroesslPaul J Dyson
May 8, 2010·Dalton Transactions : an International Journal of Inorganic Chemistry·Georg Süss-Fink
Oct 1, 2011·Chemical Communications : Chem Comm·Mary Grellier, Sylviane Sabo-Etienne
Apr 21, 2012·Chemical Communications : Chem Comm·Anna Louisa NoffkePeter J Sadler
Jun 19, 2012·Journal of Mass Spectrometry : JMS·Priscila M LalliMarcos N Eberlin
Jun 26, 2012·Dalton Transactions : an International Journal of Inorganic Chemistry·Lionel Delaude, Albert Demonceau
Aug 15, 2012·Journal of Cheminformatics·Marcus D HanwellGeoffrey R Hutchison
Mar 16, 2013·The Journal of Physical Chemistry. a·Carlos Larriba, Christopher J Hogan
Jul 10, 2014·Dalton Transactions : an International Journal of Inorganic Chemistry·Pascale Crochet, Victorio Cadierno
Jan 28, 2015·Journal of the American Society for Mass Spectrometry·Boguslaw P Pozniak, Richard B Cole
Mar 12, 2015·Journal of the American Chemical Society·Stephan WarnkeGert von Helden

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Citations

Mar 30, 2017·Dalton Transactions : an International Journal of Inorganic Chemistry·Dieter Cremer, Elfi Kraka
Jul 1, 2017·Dalton Transactions : an International Journal of Inorganic Chemistry·Tomás F BeltránLionel Delaude
Feb 2, 2019·Mass Spectrometry Reviews·Valérie GabelicaThomas Wyttenbach
Nov 8, 2016·International Journal for Ion Mobility Spectrometry : Official Publication of the International Society for Ion Mobility Spectrometry·Paolo BenigniFrancisco Fernandez-Lima
Feb 24, 2018·The Journal of Chemical Physics·Tianyang WuCarlos Larriba-Andaluz
Jul 7, 2021·Analytical Chemistry·Thomas AuthKonrad Koszinowski
Jan 13, 2022·Journal of the American Society for Mass Spectrometry·Jean R N HalerEdwin De Pauw

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