Mar 27, 2020

Structural and functional footprint of visual snow syndrome

Brain : a Journal of Neurology
Christoph SchankinPeter J Goadsby


Patients with visual snow syndrome suffer from a continuous pan-field visual disturbance, additional visual symptoms, tinnitus, and non-perceptional symptoms. The pathophysiology of visual symptoms might involve dysfunctional visual cortex. So far, the extra-visual system has not been investigated. We aimed at identifying structural and functional correlates for visual and non-visual symptoms in visual snow syndrome. Patients were compared to age- and sex-matched controls using 18F-2-fluoro-2-deoxy-d-glucose PET (n = 20 per group) and voxel-based morphometry (n = 17 per group). Guided by the PET results, region of interest analysis was done in voxel-based morphometry to identify structural-functional correspondence. Grey matter volume was assessed globally. Patients had corresponding hypermetabolism and cortical volume increase in the extrastriate visual cortex at the junction of the right lingual and fusiform gyrus. There was hypometabolism in the right superior temporal gyrus and the left inferior parietal lobule. Patients had grey matter volume increases in the temporal and limbic lobes and decrease in the superior temporal gyrus. The corresponding structural and functional alterations emphasize the relevance of the visual a...Continue Reading

  • References
  • Citations


  • We're still populating references for this paper, please check back later.
  • References
  • Citations


  • This paper may not have been cited yet.

Mentioned in this Paper

Mental Suffering
Gray Matter
Cruciate Ligament
Cerebral Cortex
Left Inferior Parietal Lobule
Positron-Emission Tomography
Limbic System

Related Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Related Papers

Archivos de la Sociedad Española de Oftalmología
V M Asensio-Sánchez
Der Nervenarzt
U Beyer, C Gaul
Current Neurology and Neuroscience Reports
Abby I Metzler, Carrie E Robertson
Current Opinion in Neurology
Francesca PuleddaPeter J Goadsby
© 2020 Meta ULC. All rights reserved