Structural and functional maturation of skin during metamorphosis in the Atlantic halibut (Hippoglossus hippoglossus)

Cell and Tissue Research
Ricardo N AlvesDeborah M Power

Abstract

To establish if the developmental changes in the primary barrier and osmoregulatory capacity of Atlantic halibut skin are modified during metamorphosis, histological, histochemical, gene expression and electrophysiological measurements were made. The morphology of the ocular and abocular skin started to diverge during the metamorphic climax and ocular skin appeared thicker and more stratified. Neutral mucins were the main glycoproteins produced by the goblet cells in skin during metamorphosis. Moreover, the number of goblet cells producing neutral mucins increased during metamorphosis and asymmetry in their abundance was observed between ocular and abocular skin. The increase in goblet cell number and their asymmetric abundance in skin was concomitant with the period that thyroid hormones (THs) increase and suggests that they may be under the control of these hormones. Several mucin transcripts were identified in metamorphosing halibut transcriptomes and Muc18 and Muc5AC were characteristic of the body skin. Na+, K+-ATPase positive (NKA) cells were observed in skin of all metamorphic stages but their number significantly decreased with the onset of metamorphosis. No asymmetry was observed between ocular and abocular skin in NKA...Continue Reading

References

Jun 1, 1988·Pharmaceutical Research·G M Grass, S A Sweetana
Jul 10, 1999·Cell and Tissue Research·A J van der HeijdenS E Wendelaar Bonga
Nov 5, 1999·The Journal of Biological Chemistry·J Perez-Vilar, R L Hill
Jan 22, 2000·General and Comparative Endocrinology·A M Schreiber, J L Specker
Apr 5, 2000·The Journal of Clinical Investigation·A M DelanyE Canalis
Jul 26, 2000·Molecular Biology and Evolution·J L DesseynA Laine
Oct 2, 2001·Frontiers in Bioscience : a Journal and Virtual Library·N MoniauxS K Batra
Jul 13, 2002·The Journal of Experimental Zoology·Jonathan M Wilson, Pierre Laurent
Nov 8, 2002·Biochimica Et Biophysica Acta·W S Marshall, T D Singer
May 15, 2003·Endocrinology·Anne M DelanyErnesto Canalis
Apr 1, 1964·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·R LEV, S S SPICER
May 3, 2005·General and Comparative Endocrinology·M D EstêvãoD M Power
Sep 6, 2005·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Stamatis VarsamosGuy Charmantier
Dec 24, 2005·Physiological Reviews·Mary Callaghan Rose, Judith A Voynow
Jul 10, 2007·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Sangeetha SubramanianNeil W Ross
Dec 11, 2007·Molecular and Cellular Endocrinology·Malyka Galay-BurgosGlen E Sweeney
Mar 18, 2008·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Sangeetha SubramanianShawna L MacKinnon
Apr 24, 2008·Matrix Biology : Journal of the International Society for Matrix Biology·Josep RotllantShao-Jun Du
Sep 12, 2008·Veterinary Immunology and Immunopathology·Pilar Alvarez-Pellitero
Dec 2, 2008·Experimental Dermatology·Ehrhardt ProkschJens-Michael Jensen
Jul 11, 2009·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Ryohei YanagieToyoji Kaneko
Feb 18, 2010·Experimental Dermatology·Sebastian RakersRalf Paus
Apr 25, 2012·Marine Biotechnology·Giulia MicallefSamuel A M Martin

❮ Previous
Next ❯

Datasets Mentioned

BETA
AJ564190

Methods Mentioned

BETA
dissection
electrophoresis
biopsies

Software Mentioned

BLAST
Illustrator for
MEGA
BLASTx
SigmaPlot
Clustal W

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.