Structural and functional neuroimaging in intractable epilepsy

Neurology India
Swati ChinchureBejoy Thomas

Abstract

Medical management remains unsatisfactory in about a third of patients with epilepsy and some of them are candidates for resective epilepsy surgery. Structural and functional neuroimaging plays an important role in the identification of the precise cortical region responsible for seizures and is very crucial for a good surgical outcome. Furthermore, identification of eloquent cortical areas near the region to be resected is essential to avoid postoperative neurologic deficit. The magnetic resonance imaging (MRI) protocol for epilepsy can be individually tailored depending on the seizure semiology and possibly electroencephalography. New MRI techniques demonstrate the structure of the brain in fine detail, help in understanding the underlying pathology, and demonstrate functional activity of the brain with high spatial and temporal resolution. Metabolic imaging techniques, such as positron emission tomography (PET) and single photon emission tomography (SPECT) visualize metabolic alterations of the brain in the ictal and interictal states. In MR-negative epilepsy patients, these techniques may have localizing value. The proper use and interpretation of the findings provided by these new technologies is crucial. In this review ar...Continue Reading

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Citations

Oct 15, 2013·Clinical Neurology and Neurosurgery·Vikas DhimanSusarla K Shankar
Sep 8, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·Zuo FangYao Shulin
Oct 29, 2011·Neuroimaging Clinics of North America·Swati Chinchure, Chandrasekharan Kesavadas
Dec 31, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Zhaoxuan HeFang Zeng

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