Structural and Functional Reorganization Within Cognitive Control Network Associated With Protection of Executive Function in Patients With Unilateral Frontal Gliomas

Frontiers in Oncology
Yong LiuJiu Chen

Abstract

Background: The cognitive control network (CCN) is widely considered to be a frontoparietal circuit that is involved in executive function. This study aimed to investigate the structural and functional plasticity within the CCN in unilateral frontal gliomas, which are associated with the protection of executive functions. Methods: To detect structural and functional changes within the CCN, we measured gray matter (GM) volume, regional homogeneity, the amplitude of low-frequency fluctuation (ALFF), degree centrality, and functional connectivity within the CCN in 37 patients with gliomas invading the left frontal lobe (n = 16) or the right frontal lobe (n = 21) and 40 healthy controls (CNs). Partial correlation analysis was performed to assess the association between the altered structural and functional indices and executive function. Results: When the tumor invaded the left frontal lobe, the patients showed reduced ALFF in the dorsal medial prefrontal cortex (dmPFC) within the CCN and increased ALFF in the right superior parietal cortex (rSP) within the CCN compared to the CNs. When the tumor invaded the right frontal lobe, the patients showed significantly increased GM volume and ALFF in the left superior parietal cortex (lSP)...Continue Reading

References

May 8, 2002·Nature Reviews. Neuroscience·Maurizio Corbetta, Gordon L Shulman
Apr 28, 2004·NeuroImage·Yufeng ZangLixia Tian
Jul 8, 2005·Cerebral Cortex·Eveline A CroneSilvia A Bunge
Nov 10, 2005·Annals of Neurology·Fabrice BartolomeiCornelis J Stam
Jan 27, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Katsuyuki Sakai, Richard E Passingham
Nov 24, 2006·Brain : a Journal of Neurology·Michel DesmurgetHugues Duffau
Mar 3, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·William W SeeleyMichael D Greicius
Jun 20, 2007·Proceedings of the National Academy of Sciences of the United States of America·Nico U F DosenbachSteven E Petersen
Sep 27, 2007·Annals of Neurology·Adrian G GuggisbergSrikantan S Nagarajan
Mar 8, 2008·Stroke; a Journal of Cerebral Circulation·Lynne V GauthierGitendra Uswatte
Feb 13, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Randy L BucknerKeith A Johnson
Apr 21, 2009·Neuron·William W SeeleyMichael D Greicius
Jun 13, 2009·PLoS Computational Biology·Jeffrey AlstottOlaf Sporns
Jun 24, 2009·Cerebral Cortex·Hua-Dong XiangPeter Hagoort
Jul 22, 2009·Proceedings of the National Academy of Sciences of the United States of America·Stephen M SmithChristian F Beckmann
Nov 3, 2010·Neuron·Bradley VoytekRobert T Knight
Dec 18, 2010·AJNR. American Journal of Neuroradiology·E PravatàM Caulo
Mar 24, 2011·Brain : a Journal of Neurology·Sylvie BellevilleSerge Gauthier
Apr 15, 2011·Brain : a Journal of Neurology·Alexander DrzezgaReisa A Sperling
Oct 5, 2011·Cerebral Cortex·Xi-Nian ZuoMichael P Milham
Nov 15, 2011·Neuron·Eran Dayan, Leonardo G Cohen
May 5, 2012·AJNR. American Journal of Neuroradiology·C BrigantiM Caulo
Jun 30, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mathew R BrierBeau M Ances
Sep 3, 2013·NeuroImage·Jonathan D PowerSteven E Petersen
Sep 15, 2014·Diagnostic and Interventional Imaging·H Duffau
Apr 15, 2016·Neuroinformatics·Chao-Gan YanYu-Feng Zang
Aug 30, 2016·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jiu ChenZhijun Zhang
Nov 15, 2017·Proceedings of the National Academy of Sciences of the United States of America·Alessia CeleghinMarco Tamietto
Nov 25, 2017·Seminars in Cancer Biology·Olga Gusyatiner, Monika E Hegi
Mar 5, 2018·Neurobiology of Learning and Memory·Ana Paula CrestaniJorge Alberto Quillfeldt

❮ Previous
Next ❯

Methods Mentioned

BETA
surgical resection

Software Mentioned

MATLAB2013b
native
Statistical Parametric Mapping ( SPM12
DARTEL
ALFF
DPABI

Related Concepts

Related Feeds

Bradyarrhythmias

Bradyarrhythmias are slow heart rates. Symptoms may include syncope, dizziness, fatigure, shortness of breath, and chest pains. Find the latest research on bradyarrhythmias here.

© 2022 Meta ULC. All rights reserved