Structural brain aging and speech production: a surface-based brain morphometry study

Brain Structure & Function
Pascale Tremblay, Isabelle Deschamps

Abstract

While there has been a growing number of studies examining the neurofunctional correlates of speech production over the past decade, the neurostructural correlates of this immensely important human behaviour remain less well understood, despite the fact that previous studies have established links between brain structure and behaviour, including speech and language. In the present study, we thus examined, for the first time, the relationship between surface-based cortical thickness (CT) and three different behavioural indexes of sublexical speech production: response duration, reaction times and articulatory accuracy, in healthy young and older adults during the production of simple and complex meaningless sequences of syllables (e.g., /pa-pa-pa/ vs. /pa-ta-ka/). The results show that each behavioural speech measure was sensitive to the complexity of the sequences, as indicated by slower reaction times, longer response durations and decreased articulatory accuracy in both groups for the complex sequences. Older adults produced longer speech responses, particularly during the production of complex sequence. Unique age-independent and age-dependent relationships between brain structure and each of these behavioural measures were ...Continue Reading

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Citations

Oct 27, 2016·Journal of the American Geriatrics Society·Mylène Bilodeau-Mercure, Pascale Tremblay
Mar 7, 2017·Human Brain Mapping·Pascale TremblayIsabelle Deschamps
Nov 6, 2018·Frontiers in Neuroscience·Jingting LiHanjun Liu
Sep 26, 2019·Frontiers in Human Neuroscience·Jakolien den HollanderRoelien Bastiaanse

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