Structural characterization of a novel xylolipid biosurfactant from Lactococcus lactis and analysis of antibacterial activity against multi-drug resistant pathogens

Bioresource Technology
P Saravanakumari, K Mani

Abstract

Control of emerging multi-drug resistant bacteria is one of the major prerequisite in the management of opportunistic infections. Current research is focused towards the identification of effective control agents from biological origin without any alarming side effects. Lactococcus lactis, probiotic organisms was isolated and purified biosurfactant from the bacteria exhibited surface active and emulsification activities comparable to the standard biosurfactant producing bacteria Bacillus licheniformis MTCC 429. Co-culturing of the isolate with the standard organism increased the biosurfactant production and surfactant activity. Biosurfactant from the L. lactis was characterized as glycolipids which consist of Methyl-2-O-methyl-beta-d-xylopyranoside with octadecanoic acid with a cumulative molecular weight of approximately 476g/mol by GC-MS and NMR studies. Purified biosurfactants showed broad range of antibacterial activity and are safe to administrate orally and dermally. So it could be used as a therapeutic agent in pharmaceutical or as a preservative in food industries.

References

Feb 1, 1995·Environmental Health Perspectives·R M Miller
Apr 25, 2001·Applied Biochemistry and Biotechnology·I GrangemardF Peypoux
Feb 18, 2004·Journal of Microbiological Methods·Noha H YoussefMichael J McInerney
Jul 9, 2004·Applied and Environmental Microbiology·Lígia RodriguesRosário Oliveira
Sep 19, 2008·Marine Pollution Bulletin·Maria Nikolopoulou, Nicolas Kalogerakis
Sep 1, 1995·Environmental Science & Technology·D C HermanR M Miller

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Citations

May 1, 2013·Critical Reviews in Food Science and Nutrition·Paulraj KanmaniVenkatesan Arul
Dec 17, 2014·TheScientificWorldJournal·Deepansh SharmaSuresh Procha
Sep 14, 2014·Applied Biochemistry and Biotechnology·Hamidreza HajfarajollahKambiz Akbari Noghabi
Jan 9, 2016·Current Microbiology·Anila Fariq, Ayesha Saeed
May 15, 2015·Letters in Applied Microbiology·A Varvaresou, K Iakovou
Sep 12, 2015·Carbohydrate Research·Mnif Inès, Ghribi Dhouha
Apr 23, 2016·Applied Microbiology and Biotechnology·Eleonora CiandriniWally Baffone
Sep 11, 2012·Microbiological Research·Alejandro de Jesús Cortés-SánchezMaría Eugenia Jaramillo-Flores
Sep 27, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Abdolrazagh MarzbanAbolghasem Danesh
Aug 19, 2018·Biotechnology and Applied Biochemistry·Hamidreza HajfarajollahKambiz Akbari Noghabi
Aug 21, 2013·Biotechnology Progress·Jenyffer Medeiros CamposIbrahim M Banat
Jun 6, 2020·Frontiers in Microbiology·Tetyana Milojevic, Wolfram Weckwerth
Jul 28, 2019·Genes·Jingjing LiuXiaofeng Song
Apr 28, 2019·Food Microbiology·Lionel Kenneth DygicoCatherine M Burgess
Sep 18, 2021·Proceedings of the National Academy of Sciences of the United States of America·Judy Q YangHoward A Stone

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