Structural characterization of an acidic Epimedium polysaccharide and its immune-enhancement activity

Carbohydrate Polymers
Yi WuYuanliang Hu

Abstract

One acidic polysaccharide named EPS-1 was isolated from the aqueous extract of the leaves of Epimedium acuminatum Franch. It may be composed of 1,4-linked α-d-GalpA, 1,3,4-linked α-d-GalpA, 1,6-linked β-d-Galp and terminal α-l-Rhap residues in a molar ratio of 11.0:1.0:1.0:1.0 by chemical and spectroscopic analysis. EPS-1 possessed immune modulation effects on peripheral T lymphocyte and immature chBM-DCs such as promoting the proliferation and cytokine secretion of these cells and increasing the phagocytosis ability of immature chBM-DCs.

References

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Jul 24, 2013·Veterinary Immunology and Immunopathology·Jinfeng LiangQian Yang
Jun 20, 2014·International Journal of Biological Macromolecules·Jingjuan MengFengping Shan
Sep 8, 2015·Carbohydrate Polymers·Yunpeng FanXiaoping Song

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Citations

Apr 8, 2017·International Journal of Biological Macromolecules·Yi WuDeyun Wang
Feb 20, 2019·Journal of the Science of Food and Agriculture·Hao HuangGui-Tang Chen
Sep 11, 2019·Chinese Journal of Integrative Medicine·Yu-Tong Liu, Wen-Liang Lv
Aug 31, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yan RenAntonio Del Rio Flores
Apr 8, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Jin HeCheng Peng
Jun 25, 2021·International Journal of Biological Macromolecules·Qiongxin LiangWenyi Kang
Oct 11, 2017·Journal of Agricultural and Food Chemistry·Zhuo-Er ChenHailiqian Taoerdahong
Jul 30, 2020·European Journal of Pharmacology·Yanzheng XieJinyang He

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