Structural components involved in plastid protein import

Essays in Biochemistry
Serena SchwenkertJ Soll

Abstract

Import of preproteins into chloroplasts is an essential process, requiring two major multisubunit protein complexes that are embedded in the outer and inner chloroplast envelope membrane. Both the translocon of the outer chloroplast membrane (Toc), as well as the translocon of the inner chloroplast membrane (Tic) have been studied intensively with respect to their individual subunit compositions, functions and regulations. Recent advances in crystallography have increased our understanding of the operation of these proteins in terms of their interactions and regulation by conformational switching. Several subdomains of components of the Toc translocon have been studied at the structural level, among them the polypeptide transport-associated (POTRA) domain of the channel protein Toc75 and the GTPase domain of Toc34. In this review, we summarize and discuss the insight that has been gained from these structural analyses. In addition, we present the crystal structure of the Toc64 tetratrico-peptide repeat (TPR) domain in complex with the C-terminal domains of the heat-shock proteins (Hsp) Hsp90 and Hsp70.

References

Jun 19, 1995·FEBS Letters·M Seedorf, J Soll
Dec 23, 1998·Proceedings of the National Academy of Sciences of the United States of America·B BölterR Wagner
Mar 22, 2000·The Journal of Cell Biology·K Sohrt, J Soll
Apr 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·N SveshnikovaE Schleiff
Apr 12, 2001·Plant Physiology·D Jackson-Constan, K Keegstra
Sep 19, 2001·Nature·W MartinK V Kowallik
Dec 26, 2001·Nature Structural Biology·Yuh-Ju SunChwan-Deng Hsiao
Jan 5, 2002·The Journal of Biological Chemistry·Hrvoje Fulgosi, Jurgen Soll
Feb 20, 2003·The Journal of Cell Biology·Enrico SchleiffRoswitha Harrer
Apr 1, 2003·Proceedings of the National Academy of Sciences of the United States of America·Enrico SchleiffJürgen Soll
May 14, 2003·Biochemistry·Marko JelicEnrico Schleiff
Oct 16, 2003·Trends in Biochemical Sciences·Luis Sánchez-PulidoAlfonso Valencia
Jan 22, 2004·Nature Reviews. Genetics·Jeremy N TimmisWilliam Martin
Feb 7, 2004·The EMBO Journal·Thomas BeckerEnrico Schleiff
Apr 1, 2004·The Plant Journal : for Cell and Molecular Biology·Diane ConstanPaul Jarvis
Apr 20, 2004·Molecular Biology of the Cell·Yordanka IvanovaDanny J Schnell
Aug 30, 2005·Trends in Biochemical Sciences·Stefan A PaschenDoron Rapaport
Nov 9, 2005·The Journal of Cell Biology·Kentaro InoueMasaru Ohme-Takagi
Nov 30, 2005·Molecular Microbiology·Ian E GentleTrevor Lithgow
Jan 31, 2007·The Journal of Biological Chemistry·L Evan ReddickBarry D Bruce
Feb 20, 2007·Journal of Molecular Biology·Soumya QbadouEnrico Schleiff
Mar 6, 2007·The Journal of Biological Chemistry·Yi-Hung YehChwan-Deng Hsiao
Mar 31, 2007·Journal of Biomedical Science·Hsou-Min LiChwan-Deng Hsiao
Mar 5, 2008·Annual Review of Plant Biology·Sven B GouldGeoffrey I McFadden
May 15, 2008·Nature Reviews. Molecular Cell Biology·Christine S WeirichYves Barral
May 20, 2008·Journal of Experimental Botany·Mislav OrebEnrico Schleiff
Jun 11, 2008·The Journal of Biological Chemistry·Patrick KoenigIvo Tews
Feb 4, 2009·The Journal of Biological Chemistry·Birgit AgneFelix Kessler

❮ Previous
Next ❯

Citations

Sep 13, 2018·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Anne KönnelKatrin Philippar
Nov 16, 2019·Journal of Experimental Botany·Lynn G L Richardson, Danny J Schnell
Feb 13, 2020·Plants·Fabian RiesFelix Willmund
May 30, 2020·International Journal of Molecular Sciences·Nathan W Van BibberVladimir N Uversky
Oct 7, 2020·International Journal of Molecular Sciences·Sebastian Kreimendahl, Joachim Rassow

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
Patrick K O'NeilDanny J Schnell
Biochemical Society Transactions
K ChenDanny J Schnell
Biochimica Et Biophysica Acta
Charles AndrèsFelix Kessler
© 2022 Meta ULC. All rights reserved