Structural durability of early-generation Transcatheter aortic valve replacement valves compared with surgical aortic valve replacement valves in heart valve surgery: a systematic review and meta-analysis

Journal of Cardiothoracic Surgery
Ashlynn LerTheo Kofidis

Abstract

The current treatment for aortic stenosis includes open surgical aortic valve replacement (SAVR) as well as endovascular transcatheter aortic valve replacement (TAVR). This study aims to compare the 1-year, 2-3 year and 5-year structural durability of TAVR valves with that of SAVR valves. A systematic literature search was conducted in July 2019 on Medline (via PubMed), Embase and Cochrane electronic databases according to the PRISMA guidelines. Thirteen randomized controlled trials were included. From the meta-analysis, we observed higher rates of 1-year (OR: 7.65, CI: 4.57 to 12.79, p < 0.00001), 2-3-year (OR: 13.49, CI: 5.66 to 32.16, p < 0.00001) and 5-year paravalvular regurgitation (OR: 14.51, CI: 4.47 to 47.09, p < 0.00001) associated with the TAVR valves than the SAVR valves. There were also higher rates of 1-year (OR: 5.00, CI: 3.27 to 7.67, p < 0.00001), 2-3-year (OR: 8.14, CI: 3.58 to 18.50, p < 0.00001) and 5-year moderate or severe aortic regurgitation (MD: 14.65, CI: 4.55 to 47.19, p < 0.00001), and higher rates of 1-year (OR: 3.55, CI: 1.86 to 6.77, p = 0.0001), 2-3-year (OR: 3.55, CI: 1.86 to 6.77, p = 0.0001) and 5-year reintervention (OR: 3.55, CI: 1.22 to 10.38, p = 0.02) in the TAVR valves as compared to SAV...Continue Reading

References

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Citations

Aug 5, 2020·Journal of Cardiothoracic Surgery·Taufiek K RajabYasir Abu-Omar
Jan 26, 2021·Journal of Cardiac Surgery·Anoop S SumalNarain Moorjani
Nov 3, 2020·Journal of Cardiac Surgery·Donald D Glower
Jan 1, 2021·Frontiers in Cardiovascular Medicine·Pier Paolo BocchinoLuigi Biasco
May 27, 2021·Advanced Healthcare Materials·Hieu T BuiLakshmi Prasad Dasi
Oct 12, 2021·Trends in Cardiovascular Medicine·Zachary TugaoenJohn Vavalle

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Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

RevMan
GRADEpro

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