PMID: 7035346Jan 1, 1981Paper

Structural features and selective expression of three Ly-5+ cell-surface molecules

Immunogenetics
J S TungE A Boyse

Abstract

Conventional Ly-5 alloantisera precipitate cell-surface molecules of three sizes: 200K, 205K, and 220K. In SDS-PAGE, the rat monoclonal antibody 74/8' precipitates the same three molecules from both Ly-5.1 and Ly-5.2 cells. Cleveland mapping of the three molecules, precipitated by reaction of conventional Ly-5 alloantisera or 74/8' monoclonal antibody with lysates of 125I-labeled cells, disclosed no differences among the three molecular forms, but markedly distinguished all three Ly-5.1 molecules from all three Ly-5.2 molecules. Each of the three molecular forms can be expressed independently of the other two by cloned culture lines of Ly-5+ cells of different hematopoietic lineage. All of the seven cloned lines tested expressed only one form. However, two of the seven uncloned culture lines tested, plasmacytoma MOPC-70A and the X.1 putative macrophage line which originated from an SJL tumor, yielded both 200K and 205K forms.

Citations

Jan 1, 1987·Immunogenetics·M F SeldinH C Morse
Jan 1, 1988·Immunogenetics·M M ChanO Stutman
Jan 1, 1987·Immunogenetics·J S TungE A Boyse
Jan 1, 1984·Immunogenetics·J S TungE A Boyse
Jan 1, 1983·Immunogenetics·J S TungM A Palladino
Jan 1, 1990·Immunogenetics·Y SagaE A Boyse
Jan 1, 1984·Developmental and Comparative Immunology·K S Landreth, P W Kincade
Apr 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·K S LandrethS M Fu
Nov 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·F W ShenE A Boyse
Sep 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·Y SagaE A Boyse
Aug 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·M L ThomasI S Trowbridge
Aug 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·Y SagaE A Boyse
May 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·Y SagaE A Boyse
May 15, 1990·International Journal of Cancer. Journal International Du Cancer·R DolcettiM Boiocchi
Mar 1, 1987·International Reviews of Immunology·P W KincadeG Lee
Jan 1, 1982·Immunological Reviews·F W ShenJ S Tung
Jan 15, 2021·Experimental Animals·Kazuyuki Mekada, Atsushi Yoshiki
Nov 1, 1988·Molecular and Cellular Biology·Y SagaE A Boyse

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