Structural identification of highly polar nontarget contaminants in drinking water by ESI-FAIMS-Q-TOF-MS

Analytical Chemistry
Jassim Sultan, Wojciech Gabryelski

Abstract

Drinking water is a complex mixture that contains thousands of naturally occurring and anthropogenic contaminants. Liquid chromatography-mass spectrometry (LC-MS) methods have gained a tremendous popularity in monitoring nonvolatile, highly polar, and thermally labile components in drinking water. It is well recognized, however, that there are difficulties or limitations of LC-MS methods associated with (1) significant resources (time and effort) involved in sample preparation (preconcentration, fractionation, separation), (2) low screening capacity for target contaminants, and (3) insufficient capabilities for structural identification (elucidation) of nontarget contaminants. Consequently, LC-MS methods are mainly used for the detection of target contaminants (compounds identified in drinking water before), seldom for the structural identification of abundant nontarget pollutants (unidentified pollutants in drinking water), and almost never for the structural identification of nontarget components at a trace level. The paper presents a new method of electrospray ionization high field asymmetric waveform ion mobility spectrometry mass spectrometry (ESI-FAIMS-MS), which can detect a large number of water pollutants in a quick an...Continue Reading

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Citations

Feb 22, 2012·Journal of the American Society for Mass Spectrometry·Daniel G Beach, Wojciech Gabryelski
Jul 21, 2009·Journal of the American Society for Mass Spectrometry·Ridha MabroukiRichard D Smith
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Jan 31, 2007·Journal of Mass Spectrometry : JMS
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Aug 21, 2013·Physical Chemistry Chemical Physics : PCCP·Anton SimakovEinar Uggerud
Apr 29, 2021·Environmental Science & Technology·Gabrielle P BlackThomas M Young

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