Structural insights of mTOR complex 1

Cell Research
Hai-Xin Yuan, Kun-Liang Guan

Abstract

The mammalian target of rapamycin (mTOR), also known as the mechanistic target of rapamycin, is a central cell growth regulating kinase that forms large molecular complexes in all eukaryotic cells. A paper recently published in Science reports the architecture of mTOR complex 1 (mTORC1) and provides molecular insights into the regulation and substrate selectivity of mTORC1.

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Oct 4, 2016·Expert Review of Neurotherapeutics·Antonella TramutolaFabio Di Domenico
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