Structural modifications of the bronchial epithelium in asthma

Bulletin of Experimental Biology and Medicine
G I NepomnyashchikhM A Bakarev

Abstract

A complex of structural changes in the parenchymatous and stromal compartments, characteristic of the primary degenerative process (bronchial epithelium degeneration and subsequent diffuse atrophy, reactive sclerosis of the stroma) develops in the large bronchi in asthma. Induction of the regeneratory reactions of the bronchial epithelium with synchronously developing reorganization of the stroma (loosening of the connective tissue and stimulation of its vascularization) is shown during correction of asthma. Association of positive structural changes with lymphoid tissue hyperplasia in the bronchial wall can be interpreted in the context of significant role of lymphocytes in induction of the regeneratory reactions.

References

Nov 1, 1990·American Journal of Respiratory Cell and Molecular Biology·C E BrewsterW R Roche
Aug 1, 1989·Biulleten' eksperimental'noĭ biologii i meditsiny·A V KanonovG I Nepomniashchikh
Jul 1, 1986·Biulleten' eksperimental'noĭ biologii i meditsiny·A N ShmakovV A Trufakin
May 12, 2000·American Journal of Respiratory and Critical Care Medicine·J BousquetA M Vignola
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Jul 25, 2003·Pediatric Clinics of North America·Theresa Guilbert, Marzena Krawiec
Aug 21, 2003·The American Journal of Medicine·Stephen P Peters

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Citations

Jan 9, 2015·Annals of Medicine and Surgery·Sergei V Jargin
Apr 11, 2008·Bulletin of Experimental Biology and Medicine·D L NepomnyashchikhD V Volkova

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