PMID: 934293Jun 17, 1976Paper

Structural patterns in globular proteins

Nature
M Levitt, C Chothia

Abstract

A simple diagrammatic representation has been used to show the arrangement of alpha helices and beta sheets in 31 globular proteins, which are classified into four clearly separated classes. The observed arrangements are significantly non-random in that pieces of secondary structure adjacent in sequence along the polypeptide chain are also often in contact in three dimensions.

References

Jan 1, 1975·Progress in Biophysics and Molecular Biology·J M Baldwin
Jan 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·R J FletterickT A Steitz
Apr 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J S RichardsonD C Richardson
Jun 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·W A HendricksonK B Ward
Mar 20, 1975·Nature·K C HolmesU Gallwitz
Feb 1, 1975·Biophysical Chemistry·O B Ptitsyn, A A Rashin
Nov 5, 1975·Journal of Molecular Biology·J BergsmaJ D Smit
Apr 1, 1976·Nature·M Karplus, D L Weaver
Mar 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·D B Wetlaufer
Nov 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·M BuehnerM G Rossman
Aug 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·C I BrändénA Akeson
Jul 12, 1974·Nature·G E SchulzR H Schrimer
Jul 19, 1974·Nature·M G RossmannK W Olsen
Apr 18, 1967·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·C C BlakeV R Sarma
Sep 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·G M EdelmanJ L Wang
Nov 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·K D WatenpaughM Dubourdieu
Nov 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·R D AndersenM L Ludwig
Dec 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·R J PoljakF Saul
Oct 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·B W Matthews, S J Remington
Nov 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·D M SegalD R DAVIES
Jul 26, 1974·Nature·J W CampbellG I Hodgson
Dec 19, 1972·Biochemistry·K D Hardman, C F Ainsworth
May 15, 1973·Journal of Molecular Biology·S T Rao, M G Rossmann
Nov 6, 1973·Biochemistry·M SchifferA B Edmundson
Jul 2, 1973·Biochemical and Biophysical Research Communications·M J AdamsM G Rossmann
Dec 28, 1969·Journal of Molecular Biology·M E Goldberg
Jan 1, 1971·Advances in Protein Chemistry·F A Quiocho, W N Lipscomb
Jan 1, 1971·Advances in Protein Chemistry·J DrenthB G Wolthers
Oct 14, 1972·Journal of Molecular Biology·P M ColmanB W Matthews
Sep 1, 1971·Nature: New Biology·F S MathewsP Argos
Feb 28, 1970·Nature·D M Shotton, H C Watson
Jan 18, 1969·Nature·C S WrightJ Kraut

Citations

Jun 1, 1997·Proteins·A V Efimov
Jun 1, 1996·Biopolymers·A PerczelG D Fasman
Jan 25, 2000·Biopolymers·D M Taverna, R A Goldstein
Dec 10, 1997·Journal of Peptide Science : an Official Publication of the European Peptide Society·N NoliE Peggion
Nov 28, 2000·Biopolymers·C AnselmiP De Santis
May 1, 1992·Biopolymers·D L Weaver
Jan 1, 1991·Journal of Neuroscience Research·H Inouye, D A Kirschner
Mar 1, 1992·Protein Science : a Publication of the Protein Society·C T Zhang, K C Chou
Jun 1, 1993·Protein Science : a Publication of the Protein Society·D P Yee, K A Dill
Jul 1, 1993·Protein Science : a Publication of the Protein Society·B A MetfesselS S Rich
Dec 1, 1993·Protein Science : a Publication of the Protein Society·B I CohenF E Cohen
Apr 1, 1994·Protein Science : a Publication of the Protein Society·M Karplus, D L Weaver
Jun 1, 1994·Protein Science : a Publication of the Protein Society·N N Alexandrov, N Go
Sep 1, 1994·Protein Science : a Publication of the Protein Society·V Z SpassovR Ladenstein
Feb 1, 1995·Protein Science : a Publication of the Protein Society·X LinJ Tang
Feb 1, 1995·Protein Science : a Publication of the Protein Society·J M Chandonia, M Karplus
Mar 1, 1995·Protein Science : a Publication of the Protein Society·R Sowdhamini, T L Blundell
Apr 1, 1995·Protein Science : a Publication of the Protein Society·K A DillH S Chan
Apr 1, 1996·Protein Science : a Publication of the Protein Society·J M Chandonia, M Karplus
Sep 23, 1997·Protein Science : a Publication of the Protein Society·C J TsaiR Nussinov
Jan 7, 1998·Protein Science : a Publication of the Protein Society·S Parthasarathy, M R Murthy
Mar 26, 1998·Protein Science : a Publication of the Protein Society·R Aurora, G D Rose
Feb 9, 2002·Proteins·B Rost, V A Eyrich
Jan 1, 1990·Proteins·E G Hutchinson, J M Thornton
Jan 1, 1991·Proteins·S A Islam, D L Weaver
Oct 1, 1995·Proteins·A V FinkelsteinA M Gutin
Dec 27, 1977·Biophysics of Structure and Mechanism·B Gavish

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