PMID: 5172922Dec 1, 1971

Structural proteins of adenovirus-associated virus type 3

Journal of Virology
F B JohnsonM D Hoggan


Three major structural proteins were found in adenovirus-associated virus (AAV) type 3H virions which were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The molecular weights of the polypeptides were determined to be approximately 66,000 (VP1), 80,000 (VP2), and 92,000 (VP3). The component having a molecular weight of 66,000 comprised about 80% of the total virion protein in the major AAV-3H particle, and the other two components comprised about 10% each. Proteins of the same molecular weight were found in the minor dense AAV-3H virion, but the 80,000- and 92,000-molecular-weight components were present at about one-half the concentration. The AAV-3H virion contains about 72 molecules of VP1 and 8 and 7 molecules of VP2 and VP3, respectively.


Feb 22, 2013·Journal of Virology·Balasubramanian VenkatakrishnanMavis Agbandje-McKenna
Jan 31, 2014·Journal of Virology·Sarah C Nicolson, R Jude Samulski
Sep 21, 2019·Scientific Reports·Toyokazu KimuraMarkus Michael Bachschmid
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