Structure and evolution of the L11, L1, L10, and L12 equivalent ribosomal proteins in eubacteria, archaebacteria, and eucaryotes

Canadian Journal of Microbiology
C RamirezP P Dennis

Abstract

The genes corresponding to the L11, L1, L10, and L12 equivalent ribosomal proteins (L11e, L1e, L10e, and L12e) of Escherichia coli have been cloned and sequenced from two widely divergent species of archaebacteria, Halobacterium cutirubrum and Sulfolobus solfataricus, and the L10 and four different L12 genes have been cloned and sequenced from the eucaryote Saccharomyces cerevisiae. Alignments between the deduced amino acid sequences of these proteins and to other available homologous proteins of eubacteria and eucaryotes have been made. The data suggest that the archaebacteria are a distinct coherent phylogenetic group. Alignment of the proline-rich L11e proteins reveals that the N-terminal region, believed to be responsible for interaction with release factor 1, is the most highly conserved region and that there is specific conservation of most of the proline residues, which may be important in maintaining the highly elongated structure of the molecule. Although L11 is the most highly methylated protein in the E. coli ribosome, the sites of methylation are not conserved in the archaebacterial L11e proteins. The L1e proteins of eubacteria and archaebacteria show two regions of very high similarity near the center and the carbo...Continue Reading

Citations

Apr 1, 1994·Journal of Molecular Evolution·D Liao, P P Dennis
Jul 10, 2008·Journal of Molecular Evolution·Przemysław GrelaMarek Tchórzewski
Apr 16, 1998·Proceedings of the National Academy of Sciences of the United States of America·K SzickJ Bailey-Serres
Sep 9, 2005·Microbiology and Molecular Biology Reviews : MMBR·Jerry Eichler, Michael W W Adams
Mar 1, 1993·Journal of Cellular Biochemistry·P F OlsonJ H Fessler
Jun 17, 1998·Proceedings of the National Academy of Sciences of the United States of America·C Woese
May 18, 1999·Archives of Biochemistry and Biophysics·I KusserA T Matheson
Oct 17, 1995·Biochimica Et Biophysica Acta·A G SchijmanM J Levin
Jan 6, 1992·Biochimica Et Biophysica Acta·G HarauzD Flannigan
Mar 1, 1997·Microbiology and Molecular Biology Reviews : MMBR·P P Dennis, L C Shimmin
Oct 1, 1993·Parasitology Today·M J LevinA G Schijman

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