PMID: 9545553May 28, 1998Paper

Structure and expression of Wnt13, a novel mouse Wnt2 related gene

Mechanisms of Development
L ZakinP Brulet

Abstract

We have identified a novel mouse member of the Wnt family, Wnt13. Among mouse Wnt genes, Wnt13 is most closely related to Wnt2. Sequence comparisons and chromosomal localization strongly suggest that Wnt13, rather than Wnt2, is the mouse orthologue of both the human WNT13 and Xenopus XWnt2 genes. Wnt13 is expressed in the embryonic mesoderm during gastrulation. At later stages, transcripts are detected in the dorsal midline of the diencephalon and mesencephalon, the heart primordia, the periphery of the lung bud and the otic and optic vesicles. These data suggest that Wnt13 function might partially overlap with those of other Wnt genes in the cell signaling mechanisms controlling mesoderm specification during gastrulation and some aspects of brain, heart and lung formation.

References

Jun 26, 1992·Cell·R Nusse, H E Varmus
Nov 1, 1990·The Journal of Heredity·X Montagutelli
Jun 29, 1995·Nature·D HenriqueD Ish-Horowicz
Aug 1, 1994·Current Opinion in Genetics & Development·B A Parr, A P McMahon
Jan 1, 1994·Genes & Development·S TakadaA P McMahon
May 1, 1997·Mechanisms of Development·Y Landesman, S Y Sokol

❮ Previous
Next ❯

Citations

Aug 17, 2000·Biochemical and Biophysical Research Communications·M KatohJ Koike
Dec 8, 2009·Pediatric Cardiology·Ying TianEdward E Morrisey
Oct 26, 2002·Brain Research. Molecular Brain Research·Nicolas DaudetGuy Rebillard
Sep 13, 2001·Current Biology : CB·T P Yamaguchi
Jun 27, 2006·Nature·Elke A OberDidier Y R Stainier
Mar 14, 2008·Development, Growth & Differentiation·Toshinori HayashiHisato Kondoh
Mar 28, 2008·Development, Growth & Differentiation·Fumi Kubo, Shinichi Nakagawa
Mar 31, 2009·American Journal of Respiratory Cell and Molecular Biology·Melanie Königshoff, Oliver Eickelberg
Jul 4, 2007·The Journal of Clinical Investigation·Ethan David CohenEdward E Morrisey
May 21, 2010·The Journal of Clinical Investigation·Felicia ChenWellington V Cardoso
Jan 22, 2000·The Journal of Clinical Investigation·Z AiG I Fishman
Dec 11, 2013·PloS One·Anna-Carin HägglundLeif Carlsson
Oct 7, 2009·Proceedings of the National Academy of Sciences of the United States of America·Kelley S Harris-JohnsonXin Sun
Sep 22, 2010·Journal of Cellular Physiology·Kimberly D Tremblay
Oct 21, 2009·The Journal of Comparative Neurology·Ulrike J Sienknecht, Donna M Fekete
May 10, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Caroline KempLuc Leyns
Feb 14, 2012·Neuroscience Letters·Tadasuke Tsukiyama, Terry P Yamaguchi
Jun 30, 2006·Mechanisms of Development·Kersti LilleväliMarjo Salminen
Oct 28, 2011·Organogenesis·Laura L Yates, Charlotte H Dean
Oct 13, 2006·Mechanisms of Development·Toshinori HayashiHisato Kondoh
Mar 28, 2006·Developmental Biology·Leonard M Eisenberg, Carol A Eisenberg
Aug 30, 2005·Developmental Biology·Charlotte H DeanLee A Niswander
Jun 6, 2008·Developmental Biology·Yongjun YinDavid M Ornitz
Aug 17, 2001·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Y LinS Vainio
Sep 15, 2004·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Othman A MohamedDaniel Dufort
Jun 20, 2003·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Hong LiuValerie A Wallace
Jan 30, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Nicholas Shackel
Dec 18, 2015·Nature Reviews. Neuroscience·Detlev ArendtHeather Marlow
Jul 9, 1999·Developmental Dynamics : an Official Publication of the American Association of Anatomists·C JasoniH Roelink
Mar 8, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·M SchubertN D Holland
Jun 8, 2001·News in Physiological Sciences : an International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society·Kirk A. Gilbert, D. Eugene Rannels
Nov 15, 2013·Development·Jörg SteinfeldAstrid Vogel-Höpker
Apr 15, 2006·Development·Wellington V Cardoso, Jining Lü
Nov 23, 2018·The Journal of Surgical Research·Yuan QuXin Zhou
Sep 5, 2006·Current Biology : CB·Zoë D BurkeDavid Tosh

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.