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Structure and Function of the AAA+ ATPase p97, a Key Player in Protein Homeostasis

Sub-cellular Biochemistry

Jan 16, 2020

Petra HänzelmannHermann Schindelin

Abstract

p97 belongs to the functional diverse superfamily of AAA+ (ATPases Associated with diverse cellular Activities) ATPases and is characterized by an N-terminal regulatory domain and two stacked hexameric ATPase domains forming a central protein conducting channel. p97 is highly versatile ...read more

Mentioned in this Paper

Adenosine Triphosphate
Coenzymes
Extracellular signal-regulated kinase 3
Nervous System Disorder
Membrane
Adenosinetriphosphatase
Chromatin
Cancer Treatment
Heat-Shock Response
Macromolecular Complexes
3
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Structure and Function of the AAA+ ATPase p97, a Key Player in Protein Homeostasis

Sub-cellular Biochemistry

Jan 16, 2020

Petra HänzelmannHermann Schindelin

PMID: 31939153

DOI: 10.1007/978-3-030-28151-9_7

Abstract

p97 belongs to the functional diverse superfamily of AAA+ (ATPases Associated with diverse cellular Activities) ATPases and is characterized by an N-terminal regulatory domain and two stacked hexameric ATPase domains forming a central protein conducting channel. p97 is highly versatile ...read more

Mentioned in this Paper

Adenosine Triphosphate
Coenzymes
Extracellular signal-regulated kinase 3
Nervous System Disorder
Membrane
Adenosinetriphosphatase
Chromatin
Cancer Treatment
Heat-Shock Response
Macromolecular Complexes
3

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Neurodegeneration: Autophagy

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Related Papers

Frontiers in Molecular Biosciences

The Interplay of Cofactor Interactions and Post-translational Modifications in the Regulation of the AAA+ ATPase p97

Frontiers in Molecular BiosciencesApril 30, 2017
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Fundamental Characteristics of AAA+ Protein Family Structure and Function

Archaea : an International Microbiological JournalOctober 6, 2016
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