Structure and function of the bovine fetomaternal unit in relation to the causes of retained fetal membranes

The Veterinary Record
A P McNaughton, R D Murray

Abstract

Approximately 5 per cent of dairy cows are affected by retained fetal membranes. Retained fetal membranes are an important risk factor for the metritis/endometritis disease complex occurring in early lactation, and costs the UK dairy industry approximately pound16 million annually in lost production. Veterinary clinicians have described the clinical signs, treatment and some associated risk factors of the condition since early Victorian times, and these have not changed over time. Research carried out within the past 20 years suggests that there is an immunological basis for retained fetal membranes. In a normal calving, the maturation of the placenta and its separation from healthy caruncles depends upon incompatibility between maternal and fetal major histocompatibility complex class I expressed on epithelium within the fetomaternal unit. Placental maturation follows stimulation of the maternal immune response and the production of neutrophil-activating factors within the epithelium in the caruncular arcade. This affects the extracellular matrix components within the placentome, breaking down collagen within the chorionic villi and assisting in separation from the caruncle. Factors influencing normal placental maturation incl...Continue Reading

References

Jun 1, 1979·Journal of Animal Science·R L Prior, D B Laster
Nov 1, 1976·Endocrinology·F F BolanderR E Fellows
Nov 1, 1976·Journal of Dairy Science·W E JulienA L Moxon
Jan 1, 1991·The Journal of Steroid Biochemistry and Molecular Biology·N TeradaK Matsumoto
Feb 1, 1991·Journal of Dairy Science·H A DeluykerA S Azari
Mar 1, 1989·Journal of Dairy Science·W L Hurley, R M Doane
May 1, 1988·Placenta·J J ErwichM J Keirse
Mar 1, 1987·Cell and Tissue Research·F B Wooding, J F Beckers
Dec 1, 1985·Biology of Reproduction·T J ReimersW Hansel
Aug 1, 1985·Journal of Dairy Science·S EgerH Schindler
Jun 1, 1974·Journal of Dairy Science·L D Muller, M J Owens
Oct 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·M ShemeshJ F Strauss
Apr 1, 1984·The Veterinary Quarterly·J W Gunnink
Apr 1, 1984·The Veterinary Quarterly·J W Gunnink
Jul 1, 1980·Journal of Reproduction and Fertility·F B Wooding, D C Wathes
Sep 1, 1994·Biology of Reproduction·R A MatamorosT J Reimers
Oct 1, 1994·Journal of Dairy Science·E Brzezinska-SlebodzinskaF C Madsen
Sep 1, 1993·Journal of Dairy Science·J K MillerF C Madsen
Nov 9, 1996·The Veterinary Record·R A Laven, A R Peters
Jul 1, 1997·The Veterinary Journal·M A Kossaibati, R J Esslemont
May 22, 1998·Journal of Dairy Science·M L KinselW G Etherington
Oct 30, 1998·Zentralblatt für Veterinärmedizin. Reihe A·M KankoferM Fidecki
Feb 13, 2001·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M Kankofer
Mar 8, 2002·Reproduction in Domestic Animals = Zuchthygiene·M MiyoshiT Iwanaga
Apr 4, 2002·Reproduction in Domestic Animals = Zuchthygiene·R A Laven, A R Peters
Apr 13, 2002·Journal of Dairy Science·Kayoko KimuraTimothy A Reinhardt

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Citations

Aug 31, 2012·Reproductive Biology and Endocrinology : RB&E·Nele SprekelerAlois Boos
Feb 27, 2013·American Journal of Veterinary Research·Alireza Heravi MoussaviRobert O Gilbert
Oct 28, 2011·Reproduction : the Official Journal of the Society for the Study of Fertility·Dominik StreylStefan Bauersachs
Jul 14, 2010·Reproduction : the Official Journal of the Society for the Study of Fertility·Sima ShenavaiGerhard Schuler
Jan 5, 2011·Research in Veterinary Science·Fu ShixinLi Xiaobing
Mar 13, 2016·Molecular Reproduction and Development·Nitin M AttupuramH Kumar
Oct 18, 2014·Animal : an International Journal of Animal Bioscience·P PiamyaC-J Chang
May 9, 2016·Theriogenology·J-D HaegerC Pfarrer
Feb 7, 2018·Veterinary Pathology·Miguel FernándezMonika Hilbe
Jul 7, 2019·Reproduction in Domestic Animals = Zuchthygiene·Jéssica BorghesiMaria Angelica Miglino
May 1, 2021·Animals : an Open Access Journal From MDPI·Satoshi HagaSanggun Roh
Aug 31, 2021·Frontiers in Veterinary Science·Yuqiong LiMeizhou Huang

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