Structure and function of vertebral trabecular bone

Spine
T H SmitE Schneider

Abstract

A combined morphologic and finite-element study on vertebral trabecular bone. To relate the form and function of vertebral trabecular bone, in an attempt to better understand the mechanical function of a lumbar vertebra. The architecture of bone is closely related to its mechanical function (Wolff's Law). In the human spine, vertebrae are subjected to a large variety of loads. Yet, these bones show a typical architecture, which means that they carry typical loads. Five trabecular bone cubes from specific sites of a lumbar vertebra were 3D-reconstructed for computerized analysis. The architecture of the specimens was quantified by the bone volume fraction and a measure of anisotropy, the mean bone length. A finite element model was used to calculate internal stresses within a homogeneous vertebral body under basic loads. For each load case, bone volume fraction of the specimens was compared with the equivalent von Mises stress, and mean bone length was compared with the principal stress directions. Bone volume fraction poorly related to the von Mises stress in the physiologic load case of axial compression. However, high bone volume fractions exist at locations where multiple load situations occur (e.g., near the pedicles and en...Continue Reading

Citations

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