Structure and functional analysis of the multistress response gene DDR2 from Saccharomyces cerevisiae

Biochemical and Biophysical Research Communications
N KobayashiK McEntee

Abstract

The DDR2 gene is a multistress response gene in Saccharomyces cerevisiae that is transcriptionally activated by more than thirteen xenobiotic agents and environmental or physiological stresses. The DDR2 gene encodes a small hydrophobic 61 amino acid polypeptide located on chromosome XV adjacent to the SPE2 locus. Disruption alleles of the DDR2 gene have been constructed and these ddr2 delta mutants show no defect in heat shock recovery or thermotolerance and appear normal for DNA damage sensitivity and mutagenesis.

Citations

Jan 18, 2008·Molecular Biology of the Cell·Anthony D AragonMargaret Werner-Washburne
Mar 4, 2014·PLoS Computational Biology·Lingxue Zhang, Seyoung Kim
Nov 9, 2006·Bioscience, Biotechnology, and Biochemistry·Hiromi Nishida
Dec 18, 2004·Environmental and Molecular Mutagenesis·Deborah J KeszenmanElia Nunes
Jun 23, 2004·The Journal of Biological Chemistry·Quirine LismanJoost C M Holthuis
Nov 9, 2012·The Journal of Biological Chemistry·Christian MillerPatrick Cramer

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