Structure and substrate specificity of acetyltransferase ACIAD1637 from Acinetobacter baylyi ADP1

Biochimie
Anna M DaviesPaul R Brown

Abstract

Gene ACIAD1637 from Acinetobacter baylyi ADP1 encodes a 182 amino acid putative antibiotic resistance protein. The structure of this protein (termed acepita) has been solved in space group P(2) to 2.35 A resolution. Acepita belongs to the GCN5-related N-acetyltransferase (GNAT) family, and contains the four sequence motifs conserved among family members. The structure of acepita is compared with that of pita, its homologue from Pseudomonas aeruginosa. Acepita has a similar substrate profile to pita and performs a similar function.

Citations

Jan 29, 2016·Biochemistry·Lorenza FavrotOlivia Vergnolle
Oct 28, 2016·Chemical Reviews·Geoff P Horsman, David L Zechel
Oct 4, 2016·Applied and Environmental Microbiology·Chelsey M VanDrisseJorge C Escalante-Semerena
Apr 18, 2019·Communications Biology·Venkadesh Sarkarai NadarMasafumi Yoshinaga
Apr 17, 2020·Microbiology and Molecular Biology Reviews : MMBR·Rachel M Burckhardt, Jorge C Escalante-Semerena
Jan 12, 2020·Communications Biology·Venkadesh Sarkarai NadarMasafumi Yoshinaga

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Related Papers

Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
Anna M DaviesPaul R Brown
Applied and Environmental Microbiology
Adityarup ChakravortyLeslie A Gregg-Jolly
© 2021 Meta ULC. All rights reserved