Structure at 1.6 A resolution of the protein from gene locus At3g22680 from Arabidopsis thaliana

Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
Simon T M AllardGeorge N Phillips

Abstract

The gene product of At3g22680 from Arabidopsis thaliana codes for a protein of unknown function. The crystal structure of the At3g22680 gene product was determined by multiple-wavelength anomalous diffraction and refined to an R factor of 16.0% (Rfree = 18.4%) at 1.60 A resolution. The refined structure shows one monomer in the asymmetric unit, with one molecule of the non-denaturing detergent CHAPS {3-[(3-cholamidopropyl)dimethylammonio]-1-propane sulfonate} tightly bound. Protein At3g22680 shows no structural homology to any other known proteins and represents a new fold in protein conformation space.

References

Oct 5, 1990·Journal of Molecular Biology·S F AltschulD J Lipman
Sep 5, 1993·Journal of Molecular Biology·L Holm, C Sander
Nov 1, 1995·Proteins·T MadejS H Bryant
Mar 25, 1999·Acta Crystallographica. Section D, Biological Crystallography·T C Terwilliger, J Berendzen
Mar 25, 1999·Acta Crystallographica. Section D, Biological Crystallography·G J Kleywegt, T A Jones
May 20, 1999·Nature Structural Biology·A PerrakisV S Lamzin
Dec 10, 1999·Biochemistry·J NewmanT C Terwilliger
Aug 10, 2000·Acta Crystallographica. Section D, Biological Crystallography·B P Klaholz, D Moras
Aug 16, 2000·Acta Crystallographica. Section D, Biological Crystallography·T C Terwilliger
Sep 7, 2000·Protein Science : a Publication of the Protein Society·L JaroszewskiA Godzik
Jan 31, 2003·Proteins·Simon C LovellDavid C Richardson
Feb 22, 2003·Acta Crystallographica. Section D, Biological Crystallography·Anne-Laure GallDino Moras
Dec 21, 2004·Nucleic Acids Research·Amos BairochLai-Su L Yeh
May 26, 2005·Protein Expression and Purification·F William Studier
Oct 8, 2005·Journal of Structural and Functional Genomics·Won Bae JeonGeorge N Phillips

❮ Previous
Next ❯

Citations

Dec 11, 2014·Annual Review of Plant Biology·Marjori A MatzkeAntonius J M Matzke
Sep 4, 2019·Nature Communications·Somsakul Pop WongpaleeSteven E Jacobsen
Jan 18, 2019·Computational Biology and Chemistry·Vladimir Vélez-SegarraElsie I Parés-Matos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.