Structure determination of selaginellins G and H from Selaginella pulvinata by NMR spectroscopy

Magnetic Resonance in Chemistry : MRC
Yuan CaoQiang Wang

Abstract

Selaginellins G (1) and H (2), two new selaginellin derivatives, were isolated from the whole plant of Selaginella pulvinata. Their structures were elucidated, and complete assignments of the (1)H and (13)C NMR spectroscopic data were achieved by 1D and 2D NMR experiments (HSQC, HMBC, COSY and ROESY). Compound 1 displayed good antifungal activity against Candida albicans with an IC(50) value of 5.3 microg/ml.

References

Sep 1, 1995·Phytochemistry·G L SilvaA D Kinghorn
Apr 19, 2007·The Journal of Organic Chemistry·Li-Ping ZhangDong-Liang Cheng
Mar 26, 2010·Bioorganic & Medicinal Chemistry Letters·Yuan CaoQiang Wang

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