PMID: 6402380Jan 10, 1983Paper

Structure determination of the major asparagine-linked sugar chain of human factor VIII--von Willebrand factor

FEBS Letters
P DebeireJ F Vliegenthart

Abstract

N-glycosidically-linked glycans released by hydrazinolysis of human factor VIII/von Willebrand factor (FVIII/vWf) were separated by high-voltage electrophoresis. Five fractions were obtained, one of them representing 60% of the total amount of the N-glycosidically-linked glycans of FVIII/vWf. On the basis of the carbohydrate composition, methylation analysis and 500 MHz 1H-NMR spectroscopy, we describe the primary structure of this major glycan which is of the monosialylated and monofucosylated biantennary N-acetyllactosaminic type.

Citations

Jul 23, 2003·Journal of Thrombosis and Haemostasis : JTH·D J Bowen
Oct 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·J E SadlerE W Davie
Aug 2, 2012·The Biochemical Journal·Kevin CanisAnne Dell
Aug 15, 1991·Biochemical and Biophysical Research Communications·T MatsuiK Titani
Jul 12, 2017·Journal of Proteome Research·Ebtesam A GashashPeng George Wang
Nov 23, 2006·Journal of Thrombosis and Haemostasis : JTH·J Vermylen
Oct 13, 2016·Journal of Thrombosis and Haemostasis : JTH·J M O'SullivanJ S O'Donnell
Jun 16, 2021·Seminars in Thrombosis and Hemostasis·Soracha WardJames S O'Donnell
Jan 1, 1986·Critical Reviews in Oncology/hematology·R J HamerJ J Sixma
Feb 1, 1987·Human Pathology·T S Zimmerman, Z M Ruggeri

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