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Structure elucidation {spectroscopic, single crystal X-ray diffraction and computational DFT studies} of new tailored benzenesulfonamide derived Schiff base copper(II) intercalating complexes: Comprehensive biological profile {DNA binding, pBR322 DNA cleavage, Topo I inhibition and cytotoxic activity}

Bioorganic Chemistry

Nov 9, 2019

Zeenat AfsanFarukh Arjmand

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Abstract

New tailored copper(II)-based intercalating complexes [Cu(L1)2] (1) and [Cu(L2)2] (2) were synthesized from Schiff base scaffold HL1 and HL2(E)-4-(2-((2-hydroxy-3-methoxybenzylidene)amino)ethyl)benzenesulfonamide and (E)-4-(2-((2-hydroxybenzylidene)amino)ethyl)benzenesulfonamide, respec...read more

Mentioned in this Paper

Dental Bonding
Malignant Neoplasm of Breast
Calcium hydroxide
Copper
DNA
Cyclic Peptides
Schiff Bases
Spectrum Analysis
X-Ray Diffraction
Benzenesulfonamide
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Structure elucidation {spectroscopic, single crystal X-ray diffraction and computational DFT studies} of new tailored benzenesulfonamide derived Schiff base copper(II) intercalating complexes: Comprehensive biological profile {DNA binding, pBR322 DNA cleavage, Topo I inhibition and cytotoxic activity}

Bioorganic Chemistry

Nov 9, 2019

Zeenat AfsanFarukh Arjmand

PMID: 31735357

DOI: 10.1016/j.bio.2019.103427

Abstract

New tailored copper(II)-based intercalating complexes [Cu(L1)2] (1) and [Cu(L2)2] (2) were synthesized from Schiff base scaffold HL1 and HL2(E)-4-(2-((2-hydroxy-3-methoxybenzylidene)amino)ethyl)benzenesulfonamide and (E)-4-(2-((2-hydroxybenzylidene)amino)ethyl)benzenesulfonamide, respec...read more

Mentioned in this Paper

Dental Bonding
Malignant Neoplasm of Breast
Calcium hydroxide
Copper
DNA

Related Papers

Paper Details
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    References currently unavailable

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