Structure-function relationships of glycoprotein hormones and their subunits' ancestors

Frontiers in Endocrinology
Claire CahoreauYves Combarnous

Abstract

Glycoprotein hormones (GPHs) are the most complex molecules with hormonal activity. They exist only in vertebrates but the genes encoding their subunits' ancestors are found in most vertebrate and invertebrate species although their roles are still unknown. In the present report, we review the available structural and functional data concerning GPHs and their subunits' ancestors.

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Citations

Jun 15, 2017·The Journal of Endocrinology·Yuxin XieChristopher H K Cheng
Sep 23, 2016·The Journal of Endocrinology·Iulia PotoracAdrian F Daly
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Jul 20, 2021·Geburtshilfe und Frauenheilkunde·Fojan RafieiKhosrow Mottaghy

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Methods Mentioned

BETA
circular dichroism
X-ray
ELISA
protein folding
glycosylation
electrophoresis
glycosylations
ELISAs
GTPases
nucleotide exchange

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