PMID: 6402778Mar 1, 1983Paper

Structure of a Bacillus subtilis bacteriophage SPO1 gene encoding RNA polymerase sigma factor

Proceedings of the National Academy of Sciences of the United States of America
M Costanzo, J Pero

Abstract

Gene 28 of Bacillus subtilis bacteriophage SPO1 codes for a regulatory protein, a sigma factor known as sigma gp28, that binds to the bacterial core RNA polymerase to direct the recognition of phage middle gene promoters. middle promoters exhibit distinctive and conserved nucleotide sequences in two regions centered about 10 and 35 base pairs upstream from the start point of mRNA synthesis. Here we report the cloning of gene 28 and its complete nucleotide sequence. We infer that sigma gp28 is a 25,707-dalton protein of 220 amino acids. Neither the nucleotide sequence of gene 28 nor the inferred amino acid sequence of sigma gp28 exhibits extensive homology to the gene or protein sequence of Escherichia coli sigma factor.

References

Jan 1, 1979·Annual Review of Genetics·M Rosenberg, D Court
Nov 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·C Talkington, J Pero
Feb 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·B Vogelstein, D Gillespie
Mar 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·C Talkington, J Pero
Apr 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J PeroT D Fox
Nov 14, 1973·Nature: New Biology·I TinocoJ Bralla
Jan 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·H Klenow, I Henningsen
Oct 25, 1981·Journal of Molecular Biology·G Lee, J Pero
Aug 11, 1982·Nucleic Acids Research·J Pustell, F C Kafatos
Jan 1, 1980·Molecular & General Genetics : MGG·G LeeJ Pero
Sep 1, 1981·Cell·R Losick, J Pero

❮ Previous
Next ❯

Citations

Aug 16, 1984·Biochemical and Biophysical Research Communications·J KudohK Kurahashi
May 1, 1992·Gene·V Scarlato, M H Sayre
May 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·G E ChristieR Calendar
Aug 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·C BinnieR Losick
Aug 26, 1986·Nucleic Acids Research·M Gribskov, R R Burgess
Mar 17, 2009·Journal of Molecular Biology·Charles R StewartMarisa L Pedulla
Apr 15, 1985·Virology·J F Curran, C R Stewart
Jan 1, 1984·Journal of Virology·C R Stewart
Nov 1, 1983·Journal of Virology·M CostanzoJ Pero
Sep 1, 1986·Microbiological Reviews·R H Doi, L F Wang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.