Structure of a new pseudaminic acid-containing capsular polysaccharide of Acinetobacter baumannii LUH5550 having the KL42 capsule biosynthesis locus

Carbohydrate Research
Sof'ya N SenchenkovaYuriy A Knirel

Abstract

The capsular polysaccharide from Acinetobacter baumannii LUH5550 was studied by 1D and 2D (1)H and (13)C NMR spectroscopy. The following structure of the branched trisaccharide repeating unit was established: [structure: see text] where Pse5Ac7RHb indicates 5-acetamido-3,5,7,9-tetradeoxy-7-[(R)-3-hydroxybutanoylamino]-L-glycero-L-manno-non-2-ulosonic acid. The genes in the capsule biosynthesis locus designated KL42 are consistent with the structure established.

Citations

Jan 17, 2020·Chembiochem : a European Journal of Chemical Biology·Emily K P FlackMartin A Fascione
Sep 20, 2018·ACS Chemical Biology·Gloria AndolinaXuechen Li

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