PMID: 7811706Dec 8, 1994

Structure of polymerizable lipid bilayers VII: lateral organization of diacetylenic phosphatidylcholines with short proximal acyl chains

Biochimica Et Biophysica Acta
D G RhodesR Bittman

Abstract

As an extension of recent results (Rhodes, Xu and Bittman (1992) Biochim. Biophys. Acta 1128, 93; Hui, Xu and Bittman (1992) Langmuir 8, 2724) with a C18 diacetylenic phosphatidylcholine, bilayers of 1,2-bis(pentacosa-4,6-diynoyl)-sn-glycero-3-phosphocholine (C25) were investigated using X-ray diffraction on multibilayers and electron diffraction on Langmuir-Blodgett deposited bilayers. Monolayers of this lipid form solid (gel phase) domains at pi > 14 mN/m. Electron diffraction data indicated that the chain spacing in these domains is 4.25 A and that the chains are tilted at angle of approximately 35 degrees relative to the bilayer plane. Wide angle data from X-ray diffraction experiments indicated a similar spacing and chain tilt. Small angle data showed that the lamellar repeat was 70 A at high humidity and < or = 60 A at low humidity. The bilayer electron density profiles indicated a bilayer structure with no interdigitation. High angle reflections indicate that the principal acyl chain repeat is preserved as a function of hydration but some rearrangement occurs for other reflections. The approximately 10 A reflection corresponding to the headgroup spacing previously observed with C18-diacetylenic phosphatidylcholine bilaye...Continue Reading

References

Feb 25, 2003·Chemistry and Physics of Lipids·Silvia Alonso-RomanowskiM Cristina Taira
Mar 14, 2002·Chemical Reviews·Anja Mueller, David F O'Brien
Feb 18, 2010·Journal of Thermal Analysis and Calorimetry·Amichai YavlovichAnu Puri
Dec 10, 1999·Biophysical Journal·O S Andersen
Oct 12, 2017·PloS One·C Facundo TempranaSilvia Del Valle Alonso
Dec 10, 2003·Journal of Biomaterials Science. Polymer Edition·Kwangmeyung KimYoungro Byun

Related Concepts

Polyacetylenes
Acetylene
Electron Density
Phosphatidylcholines
Biologic Preservation
X-Ray Diffraction
Polymers
Tilt (brand of fungicide)
Calorimetry, Differential Scanning
Polydiacetylene

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