Structure Properties, Acquisition Protocols, and Biological Activities of Oleuropein Aglycone

Frontiers in Chemistry
Fangxue XuChunchao Han

Abstract

Oleuropein aglycone, which is the major phenolic component of extra virgin olive oil, is gaining popularity and importance in scientific and public communities. This paper summarizes the structure properties, acquisition protocols, and biological activities of oleuropein aglycone. There are three hydrolytic methods used to obtain oleuropein aglycone from oleuropein-enzymatic hydrolysis, acid hydrolysis, and acetal hydrolysis. Enzymatic hydrolysis can be achieved with exogenous enzymes and endogenous enzymes. In addition, the diverse pharmacological effects of oleuropein aglycone are summaried. These pharmacological effects include anti-Alzheimer's disease, anti-breast cancer, anti-inflammatory, anti-hyperglycemic, anti-oxidative, and lipid-lowering properties. Therefore, we can use hydrolysis and biological activities to study oleuropein aglycone in the future.

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Citations

Oct 30, 2020·Frontiers in Bioengineering and Biotechnology·Rosalinda MazzeiMichele Pellegrino
Oct 31, 2021·Journal of Food Biochemistry·Masood Sadiq ButtMuhammad Rizwan
Nov 14, 2021·Comprehensive Reviews in Food Science and Food Safety·Joana MadureiraLillian Barros

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Methods Mentioned

BETA
nuclear magnetic resonance
NMR
carbon magnetic resonance
electrophoresis

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