PMID: 2094284Dec 1, 1990Paper

Structure/function relationships in methylotrophic yeasts

FEMS Microbiology Reviews
W Harder

Abstract

This symposium marks the 15th anniversary of the discovery of microbodies in methylotrophic yeasts. In the intervening years much has been learned about the structure, function and biogenesis of these organelles and these advances are described. As our endeavours continued, unexpected results have confused commonly held views. This was for instance the case when microbody-minus mutants of yeasts became available which showed that some microbody matrix enzymes may be functional when present in the cytosol while others are not. At the molecular level, our understanding of structure/function relationships is also expanding. Examples are structural elements which relate to protein topogenesis and function of enzymes in different cell compartments. Other, perhaps more unusual, adaptations have also been encountered; some involve protein-protein interactions or even modified cofactors which possibly have helped methylotrophic yeasts to establish and/or maintain themselves in natural ecosystems.

References

Jan 1, 1990·Archives of Microbiology·A C DoumaW Harder
Jul 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·R ErdmannW H Kunau
Jan 1, 1989·Archives of Microbiology·M VeenhuisW Harder
May 5, 1986·Biochimica Et Biophysica Acta·P Borst
Jan 16, 1987·Cell·E Bellion, J M Goodman
Feb 1, 1987·Archives of Microbiology·K NicolayW Harder
Jan 1, 1983·Advances in Microbial Physiology·M VeenhuisW Harder
Aug 1, 1988·Applied and Environmental Microbiology·C VerduynJ P van Dijken

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Citations

Aug 28, 2019·Journal of Bacteriology·Wei Ping TeohFrancis Alonzo
Aug 6, 2015·Journal of Exercise Nutrition & Biochemistry·Wookwang Cheon, Kiwon Lim
Mar 19, 2005·International Journal of Systematic and Evolutionary Microbiology·Cletus P Kurtzman

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