Structures of the high-valent metal-ion haem-oxygen intermediates in peroxidases, oxygenases and catalases

Journal of Inorganic Biochemistry
Hans-Petter HerslethK Kristoffer Andersson

Abstract

Peroxidases, oxygenases and catalases have similar high-valent metal-ion intermediates in their respective reaction cycles. In this review, haem-based examples will be discussed. The intermediates of the haem-containing enzymes have been extensively studied for many years by different spectroscopic methods like UV-Vis, EPR (electron paramagnetic resonance), resonance Raman, Mössbauer and MCD (magnetic circular dichroism). The first crystal structure of one of these high-valent intermediates was on cytochrome c peroxidase in 1987. Since then, structures have appeared for catalases in 1996, 2002, 2003, putatively for cytochrome P450 in 2000, for myoglobin in 2002, for horseradish peroxidase in 2002 and for cytochrome c peroxidase again in 1994 and 2003. This review will focus on the most recent structural investigations for the different intermediates of these proteins. The structures of these intermediates will also be viewed in light of quantum mechanical (QM) calculations on haem models. In particular quantum refinement, which is a combination of QM calculations and crystallography, will be discussed. Only small structural changes accompany the generation of these intermediates. The crystal structures show that the compound I ...Continue Reading

References

May 1, 1976·Quarterly Reviews of Biophysics·M M Maltempo
Oct 1, 1990·Archives of Biochemistry and Biophysics·C LarroqueJ E van Lier
Jan 1, 1989·Annual Review of Pharmacology and Toxicology·F P Guengerich
May 15, 1989·Biochemical and Biophysical Research Communications·D GalarisP Hochstein
Mar 24, 1987·Biochemistry·S L EdwardsJ Kraut
Jun 5, 1987·Journal of Molecular Biology·T L PoulosA J Howard
Dec 1, 1984·Archives of Biochemistry and Biophysics·B ChanceK G Paul
Dec 16, 1997·Proceedings of the National Academy of Sciences of the United States of America·B J BahnsonJ P Klinman
Dec 24, 1997·Nature Structural Biology·M GajhedeT L Poulos
Jun 17, 1998·Free Radical Biology & Medicine·J Everse
Jan 23, 1999·The Journal of Biological Chemistry·T MatsuiY Watanabe
Oct 8, 1999·Biophysical Journal·J VojtechovskýI Schlichting
Mar 4, 2000·Science·I SchlichtingS G Sligar
Aug 18, 2000·The Journal of Biological Chemistry·T EgawaY Ishimura
Oct 29, 2000·Journal of Inorganic Biochemistry·N BecR Lange
Feb 24, 2001·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·T EgawaY Ishimura
Mar 30, 2001·The Journal of Biological Chemistry·P Jones
Apr 11, 2001·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·P P SchmidtK K Andersson
Jun 9, 2001·Antioxidants & Redox Signaling·A I AlayashR E Cashon
Nov 7, 1996·Chemical Reviews·Richard H. HolmEdward I. Solomon
Nov 7, 1996·Chemical Reviews·Masanori SonoJohn H. Dawson
Apr 6, 2002·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·H-P HerslethK K Andersson
May 25, 2002·Nature·Gunnar I BerglundJanos Hajdu
Jul 13, 2002·Journal of Computational Chemistry·Ulf RydeKristina Nilsson
Apr 15, 2003·Trends in Cardiovascular Medicine·Daniel J GarryPradeep P A Mammen
Nov 20, 2003·Journal of the American Chemical Society·Ulf Ryde, Kristina Nilsson
Jan 17, 2004·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Patrik RydbergUlf Ryde
Apr 24, 2004·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Radu Silaghi-Dumitrescu
May 26, 2004·Biochimica Et Biophysica Acta·Matthias KolbergK Kristoffer Andersson
Sep 1, 1994·Acta Crystallographica. Section D, Biological Crystallography·B A FieldsH C Freeman
Sep 1, 2004·Journal of Inorganic Biochemistry·Kristina Nilsson, Ulf Ryde

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Citations

Oct 18, 2011·Biochemistry·José M ArgüelloDaniel Raimunda
Oct 12, 2012·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Lyndal M R JensenRitimukta Sarangi
Feb 11, 2012·Antioxidants & Redox Signaling·Giel G van DoorenGeoffrey I McFadden
Sep 6, 2006·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Jimmy HeimdalUlf Ryde
Jan 16, 2007·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Malin KvistLeif Bülow
Aug 4, 2009·Current Opinion in Chemical Biology·Carrie M Wilmot, Victor L Davidson
Jul 14, 2010·British Journal of Haematology·Ronen Ben-AmiDimitrios P Kontoyiannis
Nov 1, 2015·Journal of the American Chemical Society·Curt J BougherMahdi M Abu-Omar
Jul 1, 2016·The Journal of Physical Chemistry. B·Hector D Arbelo-LopezTroy Wymore
May 16, 2017·Journal of the American Chemical Society·Lee A SolomonH Christopher Fry
Jan 29, 2009·Angewandte Chemie·Hans Martin Senn, Walter Thiel
Aug 1, 2014·Dalton Transactions : an International Journal of Inorganic Chemistry·A C BennistonM R Probert
Jan 20, 2018·The New Phytologist·Marta SenovillaManuel González-Guerrero
May 3, 2018·Physical Chemistry Chemical Physics : PCCP·Anagh MukherjeeKumar Vanka
Apr 30, 2010·Physical Chemistry Chemical Physics : PCCP·Nora BergmannEmad F Aziz
Oct 31, 2008·Chemistry & Biodiversity·Hans-Petter HerslethK Kristoffer Andersson
Sep 9, 2008·Photosynthesis Research·Brendon Conlan
Jun 15, 2007·The Journal of Biological Chemistry·Hans-Petter HerslethK Kristoffer Andersson
Mar 8, 2012·Nature Communications·Johannes HohenbergerKarsten Meyer
Nov 22, 2013·Chemical Communications : Chem Comm·Sam P de VisserUlf Ryde
Jun 13, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Fabián G Cantú ReinhardSam P de Visser

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