Studies of anti-cytomegalovirus IgG antibody positive rate and cytomegalovirus mononucleosis in adults

Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases
N TakedaK Watanabe

Abstract

We analyzed anti-Cytomegalovirus (CMV) IgG and IgM antibody (EIA) and anti-Epstein-Barr virus (EBV) viral capsid antigen (VCA) IgG and IgM antibody (FA) in adults during 1994-1999. We examined these IgM sero-positive patient's medical records, and diagnosed CMV mononucleosis and EBV mononucleosis. Anti-CMV antibody positive rates decreased from 87.6% in 1994 to 77.8% in 1999. Especially in twenties, anti-CMV antibody positive rates decreased from 65.2% in 1994 to 53.3% in 1999. On the other hand, anti-EBV VCA antibody positive rates were not changed (91-94%). Number of cases of CMV mononucleosis increased from 2 cases in 1994 to 16 cases in 1999, but EBV mononucleosis was not changed. These results suggested that increasing cases of CMV mononucleosis was influenced by decreasing anti-CMV antibody positive rate.

Citations

Mar 19, 2014·Journal of Infection and Public Health·Zainab Khalil Mohamed AljumailiWesam Suhail Najem
Mar 27, 2015·European Journal of Haematology·Tetsuo HasegawaTomonori Nakazato
May 27, 2010·Pediatrics International : Official Journal of the Japan Pediatric Society·Masao KawataniMitsufumi Mayumi
Jul 6, 2010·The Journal of Obstetrics and Gynaecology Research·Yusuke IndeToshiyuki Takeshita
Aug 12, 2014·Annals of Hematology·Tetsuo HasegawaTomonori Nakazato
Aug 28, 2019·Experimental and Therapeutic Medicine·Toshihide MaedaMasahito Shimizu

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