Mar 1, 1976

Studies of maternal plasma prolactin and amniotic fluid prolactin. Effects of chlorpromazine and prostaglandin F2alpha

Obstetrics and Gynecology
R FreemanH Schulman

Abstract

We have studied the effect of chlorpromazine and PGF2alpha on the blood and amniotic fluid levels of prolactin over a 1-hour period of time in women who were in the 14th-20th week of gestation. Following intramuscular injection of chlorpromazine, maternal plasma prolactin rose 1.0- to 2.5-fold. No significant change was noted in maternal plasma after PGF2alpha administration. Amniotic fluid prolactin declined by 6 to 56%. These changes may be dilutional.

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Mentioned in this Paper

PRL
Depression, Chemical
Amniotic Fluid - Specimen Type
Prolactin Release-Inhibiting Hormone
PRL gene
Chlorpromazine
Prolactin Measurement
Amniotic Fluid
Prolactin Binding
Amniotic Fluid Index

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