PMID: 45163Jan 1, 1979

Studies of the antibody heterogeneity in carp (Cyprinus carpio L.). I. Electrophoretic and isoelectric spectra of anti-DNP-antibodies

Acta biologica et medica Germanica
H K MachullaH Ambrosius

Abstract

Carp IgM as well as carp anti-DNP-antibodies migrate electrophoretically very well as a diffuse band into polyacrylamide gel of large pore size. The isoelectric spectra of the carp anti-DNP-antibodies are heterogeneous and show bands in the pI-range of 4.0 to 6.4. The activity of focused anti-DNP-antibodies could be demonstrated in the pI range between 5.4 to 6.4 even in high antibody dilutions. The investigated structural heterogeneity of the anti-DNP-antibodies of carp is a further proof for the phylogenetically early onset of a large antibody heterogeneity of lower vertebrates.

Related Concepts

Vertebrates
Immunoelectrophoresis
Carp antigen
Nitrobenzenes
Carp, fish
Polyacrylamide Gels
Dinitrobenzenes
CA8 gene
FAM188A gene
IgM2

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