Studies of the temporal and spatial distribution of aerosols in multi-tiered inhalation exposure chambers

American Industrial Hygiene Association Journal
H C YehC H Hobbs

Abstract

Two multi-tiered whole body inhalation exposure chambers with nominal volumes of 1 m3 (H-1000) and 2 m3 (H-2000) were evaluated for their performance in terms of the temporal and spatial distribution of test aerosols within the chamber. Parameters investigated included chamber type, single-chamber-single-aerosol generator versus two-chamber-single-aerosol generator systems, chamber air supply and exhaust systems, particle size, and aerosol diluter type. Results indicated that: 1) particle size has an effect on chamber aerosol concentration distribution, with the larger particle resulting in a higher variation; 2) the single-chamber-single-generator system is more stable than the two-chamber-single-generator system; 3) the H-2000 chamber has a lower aerosol spatial variability than the H-1000 chamber; and 4) the aerosol distribution within the chamber could be improved with the use of a newly designed diluter.

Citations

Dec 1, 1987·Toxicology·R L CarpenterC R Doarn
Jul 10, 2008·The Annals of Occupational Hygiene·W EduardK K Heldal
Jul 23, 2005·Inhalation Toxicology·Michael J OldhamMichael T Kleinman
Jan 1, 1991·Toxicologic Pathology·M A Dorato, R K Wolff

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